Okoh Sunday O, Asekun Olayinka T, Familoni Oluwole B, Afolayan Anthony J
Department of Chemistry, University of Lagos, Akoka, Lagos, Nigeria.
Nat Prod Commun. 2011 Oct;6(10):1537-41.
Morinda lucida (L.) Benth. (Rubiacae) is used in traditional medicine in many West African countries for the treatment of various human diseases. The leaves and roots of this plant were subjected to hydro-distillation to obtain volatile oils which were analyzed by high resolution GC/MS. Fifty compounds were identified in the leaf volatile oil and the major compounds were alpha-terpinene (17.8%) and beta-bisabolene (16.3%). In the root oil, 18 compounds were identified, the major constituents being 3-fluoro-p-anidine (51.8%) and hexadecanoic acid (12.0%). Antioxidant activities of the oils were examined using the DPPH, ABTS, reducing power and lipid peroxidation assays. All assays were concentration dependent with varying antioxidant potentials. The antioxidant activity of the root volatile oil of M. lucida was similar to that of the standard drugs used.
光亮巴戟天(Morinda lucida (L.) Benth.,茜草科)在许多西非国家的传统医学中用于治疗多种人类疾病。对这种植物的叶和根进行水蒸馏以获得挥发油,并用高分辨率气相色谱/质谱联用仪对其进行分析。在叶挥发油中鉴定出50种化合物,主要化合物为α-萜品烯(17.8%)和β-红没药烯(16.3%)。在根油中,鉴定出18种化合物,主要成分是3-氟对茴香胺(51.8%)和十六烷酸(12.0%)。使用DPPH、ABTS、还原能力和脂质过氧化测定法检测了这些油的抗氧化活性。所有测定均呈浓度依赖性,且抗氧化潜力各不相同。光亮巴戟天根挥发油的抗氧化活性与所用标准药物的抗氧化活性相似。