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香桃木精油通过降低大鼠血清白细胞介素-6和肿瘤坏死因子-α来抑制炎症。

Essential oil of Myrtus communis inhibits inflammation in rats by reducing serum IL-6 and TNF-alpha.

作者信息

Maxia Andrea, Frau Maria Assunta, Falconieri Danilo, Karchuli Manvendra Singh, Kasture Sanjay

机构信息

Department of Life and Environment Sciences, Botany and Botanical Garden Division, University of Cagliari, Cagliari, Italy.

出版信息

Nat Prod Commun. 2011 Oct;6(10):1545-8.

PMID:22164804
Abstract

The topical antiinflammatory activity of the essential oil of Myrtus communis L. was studied using croton oil induced ear edema and myeloperoxidase (MPO) activity in mice, and cotton pellet induced granuloma, and serum tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in rats. On topical application, the oil exhibited a significant decrease in the ear edema as well as MPO activity. The oil also inhibited cotton pellet-induced granuloma and serum TNF-alpha and IL-6. It can be concluded that the essential oil of Myrtus communis reduces leukocyte migration to the damaged tissue and exhibits antiinflammatory activity.

摘要

利用巴豆油诱导的小鼠耳水肿和髓过氧化物酶(MPO)活性、棉球诱导的大鼠肉芽肿以及大鼠血清肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6),对香桃木精油的局部抗炎活性进行了研究。局部应用时,该精油可显著减轻耳水肿以及MPO活性。该精油还可抑制棉球诱导的肉芽肿以及血清TNF-α和IL-6。可以得出结论,香桃木精油可减少白细胞向受损组织的迁移,并具有抗炎活性。

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