抗血小板药物贝前列素的全合成。
Formal synthesis of antiplatelet drug, beraprost.
机构信息
Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad, India 500 007.
出版信息
Org Lett. 2012 Jan 6;14(1):299-301. doi: 10.1021/ol203060v. Epub 2011 Dec 14.
PMID:22168301
Abstract
The first stereocontrolled and enantiospecific formal synthesis of antiplatelet drug beraprost has been achieved from readily available 1-tetralone.
摘要
从易得的 1-四氢萘酮出发，首次实现了抗血小板药物贝前列素的立体控制和对映体特异性的全合成。
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