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Animal models: Towards a myeloma mouse.

作者信息

DeWeerdt Sarah

出版信息

Nature. 2011 Dec 14;480(7377):S38-9. doi: 10.1038/480S38a.

DOI:10.1038/480S38a
PMID:22169799
Abstract
摘要

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1
Animal models: Towards a myeloma mouse.动物模型：迈向骨髓瘤小鼠模型
Nature. 2011 Dec 14;480(7377):S38-9. doi: 10.1038/480S38a.
2
Microenvironment: Neighbourhood watch.微环境：邻里守望。
Nature. 2011 Dec 14;480(7377):S48-9. doi: 10.1038/480S48a.
3
A review of current murine models of multiple myeloma used to assess the efficacy of therapeutic agents on tumour growth and bone disease.对目前用于评估治疗药物对肿瘤生长和骨病疗效的多发性骨髓瘤小鼠模型的综述。
Bone. 2015 Aug;77:57-68. doi: 10.1016/j.bone.2015.04.004. Epub 2015 Apr 11.
4
The use of animal models in multiple myeloma.动物模型在多发性骨髓瘤中的应用。
Morphologie. 2015 Jun;99(325):63-72. doi: 10.1016/j.morpho.2015.01.003. Epub 2015 Apr 17.
5
The SCID-hu myeloma model.重症联合免疫缺陷-人骨髓瘤模型
Methods Mol Med. 2005;113:183-90. doi: 10.1385/1-59259-916-8:183.
6
NOD/SCID-GAMMA mice are an ideal strain to assess the efficacy of therapeutic agents used in the treatment of myeloma bone disease.NOD/SCID-γ小鼠是评估用于治疗骨髓瘤骨病的治疗药物疗效的理想品系。
PLoS One. 2015 Mar 13;10(3):e0119546. doi: 10.1371/journal.pone.0119546. eCollection 2015.
7
Nonirradiated NOD/SCID-human chimeric animal model for primary human multiple myeloma: a potential in vivo culture system.用于原发性人类多发性骨髓瘤的非照射NOD/SCID-人类嵌合动物模型：一种潜在的体内培养系统。
Am J Pathol. 2004 Feb;164(2):747-56. doi: 10.1016/S0002-9440(10)63162-8.
8
A clinically relevant SCID-hu in vivo model of human multiple myeloma.一种具有临床相关性的人类多发性骨髓瘤的重症联合免疫缺陷-人源化（SCID-hu）体内模型。
Blood. 2005 Jul 15;106(2):713-6. doi: 10.1182/blood-2005-01-0373. Epub 2005 Apr 7.
9
Direct measurement of hypoxia in a xenograft multiple myeloma model by optical-resolution photoacoustic microscopy.通过光学分辨率光声显微镜直接测量异种移植多发性骨髓瘤模型中的缺氧情况。
Cancer Biol Ther. 2017 Feb;18(2):101-105. doi: 10.1080/15384047.2016.1276137. Epub 2017 Jan 3.
10
The C.B.17 scid mouse strain as a model for human disseminated leukaemia and myeloma in vivo.C.B.17 scid小鼠品系作为人类体内播散性白血病和骨髓瘤的模型。
Leuk Res. 1994 Jul;18(7):513-22. doi: 10.1016/0145-2126(94)90089-2.

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Recent advances in targeted drug delivery systems for multiple myeloma.多发性骨髓瘤靶向给药系统的最新进展
J Control Release. 2024 Dec;376:215-230. doi: 10.1016/j.jconrel.2024.10.003. Epub 2024 Oct 12.
2
Animal Models of Multiple Myeloma Bone Disease.多发性骨髓瘤骨病的动物模型
Front Genet. 2021 Jun 7;12:640954. doi: 10.3389/fgene.2021.640954. eCollection 2021.
3
Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria.肠道微生物组的改变通过增加氮循环细菌的相对丰度加速多发性骨髓瘤的进展。

本文引用的文献

1
A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells.一种用于人原发性多发性骨髓瘤细胞体内扩增的独特三维重症联合免疫缺陷-聚合物支架（SCID-合成人源化）模型。
Leukemia. 2011 Apr;25(4):707-11. doi: 10.1038/leu.2010.300. Epub 2011 Jan 14.
2
Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug.用缺氧激活前药 TH-302 靶向多发性骨髓瘤缺氧龛。
Blood. 2010 Sep 2;116(9):1524-7. doi: 10.1182/blood-2010-02-269126. Epub 2010 Jun 7.
3
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma.
Microbiome. 2020 May 28;8(1):74. doi: 10.1186/s40168-020-00854-5.
4
PEGylated long-circulating liposomes deliver homoharringtonine to suppress multiple myeloma cancer stem cells.聚乙二醇化长循环脂质体递送高三尖杉酯碱以抑制多发性骨髓瘤癌干细胞。
Exp Biol Med (Maywood). 2017 May;242(9):996-1004. doi: 10.1177/1535370216685008. Epub 2017 Jan 1.
5
Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft model.在小鼠异种移植模型中，采用紫杉醇纳米粒和ABCG2抗体对多发性骨髓瘤进行靶向治疗。
Oncotarget. 2015 Sep 29;6(29):27714-24. doi: 10.18632/oncotarget.4663.
6
Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells.过氧化物酶体增殖物激活受体γ激动剂的表观遗传活性增强组蛋白去乙酰化酶抑制剂对多发性骨髓瘤细胞的抗癌作用。
PLoS One. 2015 Jun 19;10(6):e0130339. doi: 10.1371/journal.pone.0130339. eCollection 2015.
7
Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation.利用同种异体干细胞移植建立小鼠移植物抗骨髓瘤模型。
PLoS One. 2014 Nov 21;9(11):e113764. doi: 10.1371/journal.pone.0113764. eCollection 2014.
8
miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells.微小RNA-29b通过启动子去甲基化诱导细胞因子信号转导抑制因子-1表达，并对多发性骨髓瘤细胞和内皮细胞的迁移发挥负向调节作用。
Cell Cycle. 2013 Dec 1;12(23):3650-62. doi: 10.4161/cc.26585. Epub 2013 Sep 25.
9
Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models.理解多发性骨髓瘤的缺氧微环境：小鼠模型的治疗意义和贡献。
Dis Model Mech. 2012 Nov;5(6):763-71. doi: 10.1242/dmm.008961.
10
Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.合成 miR-34a 模拟物作为多发性骨髓瘤的新型治疗剂：体外和体内证据。
Clin Cancer Res. 2012 Nov 15;18(22):6260-70. doi: 10.1158/1078-0432.CCR-12-1708. Epub 2012 Oct 3.
抗DKK1单克隆抗体（BHQ880）作为多发性骨髓瘤的一种潜在治疗药物。
Blood. 2009 Jul 9;114(2):371-9. doi: 10.1182/blood-2008-11-191577. Epub 2009 May 5.
4
AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies.在生发中心后恶性肿瘤的条件性小鼠模型中，MYC转基因的AID依赖性激活可诱发多发性骨髓瘤。
Cancer Cell. 2008 Feb;13(2):167-80. doi: 10.1016/j.ccr.2008.01.007.
5
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis.分化与应激反应因子XBP-1驱动多发性骨髓瘤发病机制。
Cancer Cell. 2007 Apr;11(4):349-60. doi: 10.1016/j.ccr.2007.02.015.
6
Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations.在SCID-hu小鼠体内生长的原发性骨髓瘤细胞：一种用于研究骨髓瘤及其表现的生物学特性和治疗方法的模型。
Blood. 1998 Oct 15;92(8):2908-13.