The Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Curr Microbiol. 2012 Mar;64(3):265-70. doi: 10.1007/s00284-011-0062-7. Epub 2011 Dec 16.
For this study, ten complex class 1 integron was characterized in Escherichia coli (E. coli) isolates from Zhenjiang. Among the ten isolates, five included the bla ( CTX-M-1 ) gene between orf513 and the IS 3000. Analysis the five isolates by PFGE showed that zj102 and zj562 had same patterns profiles, which suggested that the spread of a specific clone contributed to a wide dissemination of a particular type of integron; the results also indicated that the complex class 1 integron might be a potentially novel resistant gene-capturing tool kit.
本研究对镇江分离的 10 株复杂 I 类整合子的大肠杆菌(E. coli)进行了研究。在这 10 株菌中,有 5 株菌 bla(CTX-M-1)基因位于 orf513 和 IS 3000 之间。对这 5 株菌进行 PFGE 分析表明,zj102 和 zj562 具有相同的图谱,这表明特定克隆的传播有助于特定类型整合子的广泛传播;结果还表明,复杂 I 类整合子可能是一种潜在的新型抗性基因捕获工具包。