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1
Emergence of plasmid-mediated quinolone resistance in Escherichia coli in Europe.欧洲大肠杆菌中质粒介导的喹诺酮耐药性的出现。
Antimicrob Agents Chemother. 2005 Jan;49(1):71-6. doi: 10.1128/AAC.49.1.71-76.2005.
2
Diversity of genetic environment of bla(CTX-M) genes.bla(CTX-M)基因的遗传环境多样性。
FEMS Microbiol Lett. 2004 May 15;234(2):201-7. doi: 10.1016/j.femsle.2004.01.051.
3
Outbreak of extended-spectrum beta-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a French hospital.法国一家医院中出现产超广谱β-内酰胺酶VEB-1的鲍曼不动杆菌菌株暴发。
J Clin Microbiol. 2003 Aug;41(8):3542-7. doi: 10.1128/JCM.41.8.3542-3547.2003.
4
Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China.中国上海大肠埃希菌临床分离株中的质粒介导喹诺酮耐药性
Antimicrob Agents Chemother. 2003 Jul;47(7):2242-8. doi: 10.1128/AAC.47.7.2242-2248.2003.
5
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.在34中，一个含有orf513和dfrA10的复杂In5家族1类整合子。
Antimicrob Agents Chemother. 2003 Jan;47(1):342-9. doi: 10.1128/AAC.47.1.342-349.2003.
6
Genes encoding TEM-4, SHV-2, and CTX-M-10 extended-spectrum beta-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000).编码TEM-4、SHV-2和CTX-M-10超广谱β-内酰胺酶的基因由一家医院（马德里，1989年至2000年）内的多个肺炎克雷伯菌克隆携带。
Antimicrob Agents Chemother. 2002 Feb;46(2):500-10. doi: 10.1128/AAC.46.2.500-510.2002.
7
Origins of the mobile gene cassettes found in integrons.整合子中发现的移动基因盒的起源。
Trends Microbiol. 1997 Oct;5(10):389-94. doi: 10.1016/S0966-842X(97)01123-2.
8
Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination.移动基因盒与整合子：通过位点特异性重组捕获和传播基因
Mol Microbiol. 1995 Feb;15(4):593-600. doi: 10.1111/j.1365-2958.1995.tb02368.x.
9
Expression of antibiotic resistance genes in the integrated cassettes of integrons.整合子整合盒中抗生素抗性基因的表达。
Antimicrob Agents Chemother. 1995 Jan;39(1):155-62. doi: 10.1128/AAC.39.1.155.

抗生素抗性基因表达的共同区域CR1

Common region CR1 for expression of antibiotic resistance genes.

作者信息

Rodriguez-Martinez Jose-Manuel, Poirel Laurent, Canton Rafael, Nordmann Patrice

机构信息

Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris Sud, K-Bicêtre, France.

出版信息

Antimicrob Agents Chemother. 2006 Jul;50(7):2544-6. doi: 10.1128/AAC.00609-05.

DOI:10.1128/AAC.00609-05
PMID:16801441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1489766/
Abstract

The CR1 element defined by an orf513 gene encoding a putative recombinase and a recombination crossover site has been identified upstream of several antibiotic resistance genes in Enterobacteriaceae. This CR1 element was shown to bring promoter sequences that play a role in the expression of unrelated antibiotic resistance genes.

摘要

由编码假定重组酶的orf513基因和重组交叉位点定义的CR1元件已在肠杆菌科的几个抗生素抗性基因上游被鉴定出来。该CR1元件被证明携带在不相关抗生素抗性基因表达中起作用的启动子序列。