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广泛肝切除术中的残余肝功能。

Remnant liver function during surgery for extensive hepatic resection.

作者信息

Nagasue N, Inokuchi K, Iwaki A, Yukaya H, Kanashima R, Saku M, Kobayashi M

出版信息

Jpn J Surg. 1979 Jun;9(2):125-31. doi: 10.1007/BF02468847.

DOI:10.1007/BF02468847
PMID:221710
Abstract

True functional reserve of remnant liver should be determined at the same condition that contemplated hepatectomy has been performed, and this condition can be achieved before resection by temporary clamping of the inflow vessels of hepatic lobes to be removed. Using indocyanine green (ICG), the remnant liver function (RLF) was evaluated whether or not the method can be a useful indicator for or against hepatomy. In the study of healthy dogs, the RLF proved to be a reliable indicator to prospect hepatic failure which may occur after extensive resection of the liver. Then, the method was employed in nine patients who underwent 40 to 70 per cent hepatectomy. The results indicated that the RLF with ICG during surgery, if performed under stable hemodynamics, is a beneficial tool to decide the resectability in equivocal cases.

摘要

残余肝脏的真正功能储备应在设想的肝切除术已实施的相同条件下测定,而这种条件可在切除术前通过临时夹闭拟切除肝叶的流入血管来实现。使用吲哚菁绿(ICG)评估残余肝功能(RLF),以判断该方法是否可作为支持或反对肝切除术的有用指标。在对健康犬的研究中,RLF被证明是预测广泛肝切除术后可能发生的肝衰竭的可靠指标。随后,该方法应用于9例接受40%至70%肝切除术的患者。结果表明,术中在稳定血流动力学条件下进行的ICG测定的RLF,是在疑难病例中决定可切除性的有益工具。

相似文献

1
Remnant liver function during surgery for extensive hepatic resection.广泛肝切除术中的残余肝功能。
Jpn J Surg. 1979 Jun;9(2):125-31. doi: 10.1007/BF02468847.
2
Perioperative real-time monitoring of indocyanine green clearance by pulse spectrophotometry predicts remnant liver functional reserve in resection of hepatocellular carcinoma.通过脉冲分光光度法对吲哚菁绿清除率进行围手术期实时监测可预测肝细胞癌切除术中的残余肝功能储备。
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3
[Estimation of hepatic resection volume in hepatocellular carcinoma by ICG(R15) and its relation with postoperative liver failure].[通过吲哚菁绿(ICG)滞留率(R15)评估肝细胞癌肝切除体积及其与术后肝衰竭的关系]
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Evaluation of liver function for hepatic resection for hepatocellular carcinoma in the liver with damaged parenchyma.对肝实质受损的肝脏中肝细胞癌肝切除术的肝功能评估。
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Evaluation of preoperative hepatic function in patients with hepatocellular carcinoma undergoing hepatectomy.肝细胞癌肝切除患者术前肝功能评估
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6
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Comparison of the ability of Child-Pugh score, MELD score, and ICG-R15 to assess preoperative hepatic functional reserve in patients with hepatocellular carcinoma.比较Child-Pugh评分、终末期肝病模型(MELD)评分和吲哚菁绿15分钟滞留率(ICG-R15)评估肝细胞癌患者术前肝功能储备的能力。
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[Indications for limited hepatic resection in hepatocellular carcinoma].[肝细胞癌局限性肝切除术的适应证]
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10
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本文引用的文献

1
Metabolism before and after hepatic lobectomy for cancer. Studies in twenty-three patients.肝癌肝叶切除术前与术后的代谢。对23例患者的研究。
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2
MULTIPLE ADENOMA (HAMARTOMA) OF THE LIVER TREATED BY SUBTOTAL (90 PERCENT) RESECTION: MORPHOLOGICAL AND FUNCTIONAL STUDIES OF REGENERATION.经次全(90%)肝切除治疗的肝脏多发性腺瘤(错构瘤):再生的形态学与功能研究
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Enzyme and function changes after extensive liver resection in man.
人体广泛肝切除术后的酶及功能变化
Ann Surg. 1969 Jan;169(1):111-9. doi: 10.1097/00000658-196901000-00011.
4
Metabolic changes following major hepatic resection.肝大部切除术后的代谢变化
Ann Surg. 1969 Jan;169(1):102-10. doi: 10.1097/00000658-196901000-00010.
5
Clinical application of cytochrome a(plus a3) assay of mitochondria from liver specimens: an aid in determining metabolic tolerance of liver remnant for hepatic resection.肝脏标本中线粒体细胞色素a(加a3)测定的临床应用:对确定肝切除术后肝残余代谢耐受性的辅助作用
Ann Surg. 1974 Dec;180(6):868-76. doi: 10.1097/00000658-197412000-00013.
6
Metabolic function and regeneration of cirrhotic and non-cirrhotic livers after hepatic lobectomy in man.人类肝叶切除术后肝硬化和非肝硬化肝脏的代谢功能与再生
Ann Surg. 1965 Dec;162(6):959-72. doi: 10.1097/00000658-196512000-00002.
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Angiographic evaluation of hepatoma for surgical treatment.用于手术治疗的肝癌血管造影评估。
Surg Gynecol Obstet. 1976 Aug;143(2):184-90.
8
Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection.85%至90%肝切除术后出现脱发、腹水及不完全再生。
Am J Surg. 1975 May;129(5):587-90. doi: 10.1016/0002-9610(75)90323-2.
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Hepatic dearterialization for nonrespectable primary and secondary tumors of the liver.
Cancer. 1976 Dec;38(6):2593-603. doi: 10.1002/1097-0142(197612)38:6<2593::aid-cncr2820380654>3.0.co;2-6.
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Management of primary liver cell carcinoma.原发性肝细胞癌的管理
Am J Surg. 1975 Jul;130(1):33-7. doi: 10.1016/0002-9610(75)90452-3.