Nagasue N, Inokuchi K, Iwaki A, Yukaya H, Kanashima R, Saku M, Kobayashi M
Jpn J Surg. 1979 Jun;9(2):125-31. doi: 10.1007/BF02468847.
True functional reserve of remnant liver should be determined at the same condition that contemplated hepatectomy has been performed, and this condition can be achieved before resection by temporary clamping of the inflow vessels of hepatic lobes to be removed. Using indocyanine green (ICG), the remnant liver function (RLF) was evaluated whether or not the method can be a useful indicator for or against hepatomy. In the study of healthy dogs, the RLF proved to be a reliable indicator to prospect hepatic failure which may occur after extensive resection of the liver. Then, the method was employed in nine patients who underwent 40 to 70 per cent hepatectomy. The results indicated that the RLF with ICG during surgery, if performed under stable hemodynamics, is a beneficial tool to decide the resectability in equivocal cases.
残余肝脏的真正功能储备应在设想的肝切除术已实施的相同条件下测定,而这种条件可在切除术前通过临时夹闭拟切除肝叶的流入血管来实现。使用吲哚菁绿(ICG)评估残余肝功能(RLF),以判断该方法是否可作为支持或反对肝切除术的有用指标。在对健康犬的研究中,RLF被证明是预测广泛肝切除术后可能发生的肝衰竭的可靠指标。随后,该方法应用于9例接受40%至70%肝切除术的患者。结果表明,术中在稳定血流动力学条件下进行的ICG测定的RLF,是在疑难病例中决定可切除性的有益工具。