Department of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden.
J Occup Environ Med. 2011 Dec;53(12):1425-9. doi: 10.1097/JOM.0b013e3182363c17.
To perform follow-up of lung function and respiratory and ocular symptoms in foundry workers exposed to monoisocyanates using the Hot Box method.
Four years after an initial assessment, 25 foundry workers and 55 referents completed a questionnaire and were assessed by spirometry pre- and postshift. Exposure to isocyanic acid, methyl isocyanate, and formaldehyde was measured.
Exposure levels were reduced by 50% at follow-up. A high prevalence of nasal and ocular symptoms remained in both groups, but lower airway symptoms had decreased. Lung function preshift was lower for the exposed group, but lung function over shift was unaffected.
The high prevalence of nasal symptoms and the small reduction of forced expiratory volume in 1 second preshift in exposed foundry workers at follow-up may indicate a prolonged influence of previous exposure in the working environment despite reduced exposure levels at follow-up.
使用热盒法对接触单异氰酸酯的铸造工人进行肺功能和呼吸及眼部症状的随访。
初次评估 4 年后，25 名铸造工人和 55 名对照者完成了一份问卷，并在班前和班后进行了肺活量测定。测量了异氰酸、甲基异氰酸酯和甲醛的暴露水平。
随访时暴露水平降低了 50%。两组均有较高的鼻腔和眼部症状，但下呼吸道症状有所减轻。暴露组班前的肺功能较低，但班后肺功能不受影响。
暴露组工人在随访时仍存在较高的鼻部症状和班前一秒用力呼气量的小幅度下降，这可能表明尽管随访时的暴露水平有所降低，但以前在工作环境中的暴露仍有长期影响。
