Querques Giuseppe, Forte Raimondo, Souied Eric H
Créteil University Eye Clinic, 40 Avenue de Verdun, 94000 Créteil, France.
J Nutr Metab. 2011;2011:748361. doi: 10.1155/2011/748361. Epub 2011 Oct 31.
Over the last decade, several epidemiological studies based on food frequency questionnaires suggest that omega-3 polyunsaturated fatty acids could have a protective role in reducing the onset and progression of retinal diseases. The retina has a high concentration of omega-3, particularly DHA, which optimizes fluidity of photoreceptor membranes, retinal integrity, and visual function. Furthermore, many studies demonstrated that DHA has a protective, for example antiapoptotic, role in the retina. From a nutritional point of view, it is known that western populations, particularly aged individuals, have a higher than optimal omega-6/omega-3 ratio and should enrich their diet with more fish consumption or have DHA supplementation. This paper underscores the potential beneficial effect of omega-3 fatty acids on retinal diseases.
在过去十年中,多项基于食物频率问卷的流行病学研究表明,ω-3多不饱和脂肪酸在降低视网膜疾病的发病和进展方面可能具有保护作用。视网膜中ω-3,特别是DHA的浓度很高,这优化了光感受器膜的流动性、视网膜完整性和视觉功能。此外,许多研究表明,DHA在视网膜中具有保护作用,例如抗凋亡作用。从营养角度来看,已知西方人群,尤其是老年人,ω-6/ω-3比例高于最佳水平,应通过增加鱼类消费或补充DHA来丰富饮食。本文强调了ω-3脂肪酸对视网膜疾病的潜在有益作用。