Le Novère Nicolas, Hucka Michael, Anwar Nadia, Bader Gary D, Demir Emek, Moodie Stuart, Sorokin Anatoly
Stand Genomic Sci. 2011 Nov 30;5(2):230-42. doi: 10.4056/sigs.2034671.
The Computational Modeling in Biology Network (COMBINE), is an initiative to coordinate the development of the various community standards and formats in computational systems biology and related fields. This report summarizes the activities pursued at the first annual COMBINE meeting held in Edinburgh on October 6-9 2010 and the first HARMONY hackathon, held in New York on April 18-22 2011. The first of those meetings hosted 81 attendees. Discussions covered both official COMBINE standards-(BioPAX, SBGN and SBML), as well as emerging efforts and interoperability between different formats. The second meeting, oriented towards software developers, welcomed 59 participants and witnessed many technical discussions, development of improved standards support in community software systems and conversion between the standards. Both meetings were resounding successes and showed that the field is now mature enough to develop representation formats and related standards in a coordinated manner.
生物网络计算建模(COMBINE)是一项旨在协调计算系统生物学及相关领域中各种社区标准和格式开发的倡议。本报告总结了2010年10月6日至9日在爱丁堡举行的首届COMBINE年度会议以及2011年4月18日至22日在纽约举行的首届HARMONY黑客马拉松所开展的活动。首届会议有81名与会者。讨论内容涵盖了COMBINE的官方标准(生物通路交换格式、系统生物学图形符号和系统生物学标记语言),以及不同格式之间的新兴工作和互操作性。第二届会议面向软件开发人员,有59名参与者,进行了许多技术讨论,在社区软件系统中开发了改进的标准支持,并实现了标准之间的转换。这两次会议都取得了巨大成功,表明该领域目前已足够成熟,可以以协调的方式开发表示格式和相关标准。