牛促肾上腺皮质激素-β-促脂素前体克隆cDNA的核苷酸序列
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.
作者信息
Nakanishi S, Inoue A, Kita T, Nakamura M, Chang A C, Cohen S N, Numa S
出版信息
Nature. 1979 Mar 29;278(5703):423-7. doi: 10.1038/278423a0.
DOI:10.1038/278423a0
PMID:221818
Abstract
The nucleotide sequence of a 1,091-base pair cloned cDNA insert encoding bovine corticotropin-beta-lipotropin precursor mRNA is reported. The corresponding amino acid sequence indicates that the precursor protein consists of repetitive units and includes a third melanotropin sequence in its cryptic portion. Pairs of lysine and arginine residues separate the component peptides of the precursor.
摘要
报道了编码牛促肾上腺皮质激素-β-促脂解素前体mRNA的1091个碱基对克隆cDNA插入片段的核苷酸序列。相应的氨基酸序列表明，前体蛋白由重复单元组成，并且在其隐蔽部分包含第三个促黑素序列。赖氨酸和精氨酸残基对将前体的组成肽分开。
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