Cariology Unit, Department of Oral Rehabilitation, University of Talca, Chile.
Acta Odontol Scand. 2012 Dec;70(6):583-8. doi: 10.3109/00016357.2011.640287. Epub 2011 Dec 20.
Regardless of the total amount of fluoride (F) in a dentifrice, only the soluble fraction presents anti-caries activity and its concentration must be above 1000 ppm. No information regarding the quality of F in Chilean toothpastes is available. The aim of this study, therefore, was to determine the F concentration present in commercially-available toothpastes in Chile.
Eighteen toothpastes of five different brands were tested, each purchased from three different chain drugstores in Chile. For each toothpaste, total, total soluble and ionic F concentrations were assessed and expressed as ppm of F (μg F/g).
Among the dentifrices evaluated, 77.8% contained NaF (sodium fluoride), 16.7% MFP (monofluorphosphate) and 5.6% both types of F salts; 77.2% of the dentifrices showed similar total F content to that declared by the manufacturer in the labeling with only five with lower concentration than expected, beyond a 5% disagreement tolerance range. Total soluble F ranged from 958.8-1496.3 ppm (mean ± SD: 1270.5 ± 183.7). Five toothpastes showed lower total soluble F than total F. Only one toothpaste showed soluble salt levels below the recommended dose for this type of dentifrice.
Most Chilean dentifrices evaluated contained soluble F within the range of 1000-1500 ppm and, therefore, may have anti-caries activity.
无论牙膏中的氟化物（F）总量如何，只有可溶性部分具有抗龋活性，其浓度必须高于 1000ppm。目前智利市售牙膏中 F 质量的相关信息尚未可知。因此，本研究旨在测定智利市售牙膏中的 F 浓度。
共测试了五个不同品牌的 18 种牙膏，每种均从智利三家不同连锁药店购买。对每种牙膏，评估总氟、总可溶性氟和离子氟浓度，并以 F 浓度（μg F/g）表示。
在所评估的牙膏中，77.8%含有 NaF（氟化钠），16.7%含有 MFP（单氟磷酸），5.6%同时含有两种 F 盐；77.2%的牙膏的总氟含量与标签上制造商的宣称值相似，只有 5 种牙膏的浓度低于预期，超出了 5%的差异容忍范围。总可溶性 F 浓度范围为 958.8-1496.3ppm（均值±SD：1270.5±183.7）。五种牙膏的总可溶性 F 低于总 F。仅有一种牙膏的可溶性盐含量低于此类牙膏的推荐剂量。
大多数评估的智利牙膏中的可溶性 F 处于 1000-1500ppm 范围内，因此可能具有抗龋活性。
