Figueiredo Regina M P de, Naveca Felipe Gomes, Oliveira Cintia Mara, Bastos Michele de Souza, Mourão Maria Paula Gomes, Viana Suziane de S, Melo Miriam do N, Itapirema Evaulino F, Saatkamp Cassiano J, Farias Izeni P
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brazil.
Rev Inst Med Trop Sao Paulo. 2011 Nov-Dec;53(6):321-3. doi: 10.1590/s0036-46652011000600004.
The natural co-infection with dengue virus can occur in highly endemic areas where different serotypes have been observed for many years. We report here four cases of DENV-3/DENV-4 co-infection detected by serological and molecular tests among 674 patients with acute undifferentiated fever from the tropical medicine reference center of Manaus City, Brazil, between 2005 and 2010. Analysis of the sequences obtained indicated the presence of genotype 3 and 1 for DENV-3 and DENV-4 respectively.
在登革热病毒高度流行的地区，多年来已观察到不同血清型，自然共感染情况可能会发生。我们在此报告，2005年至2010年期间，在巴西马瑙斯市热带医学参考中心的674例急性未分化发热患者中，通过血清学和分子检测发现了4例DENV-3/DENV-4共感染病例。对所获得序列的分析表明，DENV-3和DENV-4分别存在基因型3和基因型1。
