巴西塞阿拉州一名患者同时感染2型登革热病毒和3型登革热病毒。
Concurrent infection with dengue virus type-2 and DENV-3 in a patient from Ceará, Brazil.
作者信息
Araújo Fernanda Montenegro de Carvalho, Nogueira Rita Maria Ribeiro, de Araújo Josélio Maria Galvão, Ramalho Izabel Letícia Cavalcante, Roriz Maria Lucia Feitosa de Sá, de Melo Maria Elizabeth Lisboa, Coelho Ivo Castelo Branco
机构信息
Laboratório Central de Saude Pública do Ceará, Fortaleza, CE, Brasil.
出版信息
Mem Inst Oswaldo Cruz. 2006 Dec;101(8):925-8. doi: 10.1590/s0074-02762006000800017.
Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed. Dual infection by DENV-2 and DENV-3 was identified by type-specific indirect immunofluorescence assay and confirmed by reverse transcription polymerase chain reaction in a patient in Ceará with a mild disease. This is the first documented case of simultaneous infection with DENV-2 and DENV-3 in Brazil. Sequencing confirmed DENV-2 and DENV-3 (South-East/American) genotype III and (SriLanka/India), genotype III respectively.
巴西多个地区曾爆发登革热疫情，经常观察到登革热病毒1型（DENV-1）、DENV-2和DENV-3共同传播。通过型特异性间接免疫荧光法在塞阿拉州一名患有轻症的患者中鉴定出DENV-2和DENV-3双重感染，并通过逆转录聚合酶链反应得到确认。这是巴西首例记录在案的DENV-2和DENV-3同时感染病例。测序分别确认DENV-2和DENV-3为（东南亚/美洲）基因型III和（斯里兰卡/印度）基因型III。
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