Pinedo-Moraleda Fernando, Tristán-Martín Belén, Dradi Giulia Greta
Department of Pathology, Hospital Universitario Fundacion Alcorcon, 28922 Alcorcon, Spain.
Department of Pathology, Hospital Nuestra Señora de Sonsoles, 05004 Avila, Spain.
J Clin Med. 2023 Jul 29;12(15):5004. doi: 10.3390/jcm12155004.
Accurately diagnosing specific variants of alopecia remains challenging for pathologists, potentially delaying appropriate therapeutic decisions by dermatologists. Issues such as limited knowledge on optimal biopsy types and processing methods add complexity. Understanding the normal histology of hair follicles and their changes throughout the follicular cycle further complicates microscopic evaluation. This paper aims to summarize these characteristics and highlight essential diagnostic clues for pathologists to confidently suggest a diagnosis, therefore playing a key role in alopecia diagnosis. Ongoing education, collaboration with dermatologists, and staying up to date on advancements is crucial for the accurate diagnosis and effective management of different types of alopecia.
准确诊断脱发的特定变体对病理学家来说仍然具有挑战性，这可能会延迟皮肤科医生做出适当的治疗决策。诸如对最佳活检类型和处理方法的了解有限等问题增加了复杂性。了解毛囊的正常组织学及其在整个毛囊周期中的变化，进一步使显微镜评估变得复杂。本文旨在总结这些特征，并突出关键的诊断线索，以便病理学家能够自信地做出诊断，从而在脱发诊断中发挥关键作用。持续教育、与皮肤科医生合作以及跟上进展对于准确诊断和有效管理不同类型的脱发至关重要。
