Boghosian Tanya, Maskan Bermudez Narges, Tosti Antonella
Washington University School of Medicine in Saint Louis, Saint Louis, MO, USA.
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Skin Appendage Disord. 2025 Jun;11(3):245-254. doi: 10.1159/000542898. Epub 2024 Dec 3.
Lichen planopilaris (LPP) is a rare scarring alopecia with poorly understood etiology, leading to challenges in both diagnosis and management. With an increasing number of studies focused on its clinical presentation, histopathology, and trichoscopic features, a comprehensive bibliometric analysis of high-impact LPP research is necessary to assess current trends and identify gaps in the literature.
The objective of this study was to analyze trends in LPP research using the top 100 most-cited articles from Web of Science.
The average number of citations per article was 80.4 (range: 37-289), with publication dates ranging from 1990 to 2021. The most-cited article was Kossard's "Progressive Frontal Scarring Alopecia in Postmenopausal Women" with 289 citations. The USA ( = 47) had the most publications, followed by England ( = 18) and Spain ( = 14). Most articles were LOE 3 ( = 34) focusing on the "clinical and histopathological presentation" ( = 33). Key reported trichoscopic features included perifollicular erythema, perifollicular scaling, and loss of follicular ostia.
This bibliometric analysis highlights foundational LPP studies, emphasizing key trichoscopic features while revealing gaps in high-level evidence. It underscores the need for more rigorous research and expanded geographic diversity to enhance diagnostic markers, refine trichoscopic criteria, and improve therapeutic approaches.
扁平苔藓性毛发角化病(LPP)是一种罕见的瘢痕性脱发,其病因尚不清楚,这给诊断和治疗带来了挑战。随着越来越多的研究聚焦于其临床表现、组织病理学和毛发镜特征,有必要对高影响力的LPP研究进行全面的文献计量分析,以评估当前趋势并找出文献中的空白。
本研究的目的是使用科学网中被引用次数最多的100篇文章来分析LPP研究的趋势。
每篇文章的平均被引用次数为80.4(范围:37 - 289),发表日期从1990年到2021年。被引用次数最多的文章是科萨德的《绝经后女性进行性额部瘢痕性脱发》,被引用289次。美国(n = 47)发表的文章最多,其次是英国(n = 18)和西班牙(n = 14)。大多数文章的证据等级为3级(n = 34),聚焦于“临床和组织病理学表现”(n = 33)。报告的关键毛发镜特征包括毛囊周围红斑、毛囊周围鳞屑和毛囊口缺失。
这项文献计量分析突出了LPP的基础研究,强调了关键的毛发镜特征,同时揭示了高级别证据中的空白。它强调需要进行更严谨的研究并扩大地理多样性,以增强诊断标志物、完善毛发镜标准并改进治疗方法。