Kołodziej Marcin, Joniec Justyna, Bartoszcze Michał, Mirski Tomasz, Gryko Romuald
Wojskowy Instytut Higieny i Epidemiologii, Ośrodek Diagnostyki i Zwalczania Zagrozeń Biologicznych, Puławy.
Przegl Epidemiol. 2011;65(3):477-82.
The efficiency of peptides against many species of bacteria, fungi and parasites has been widely described. Recent studies on peptides have also demonstrated their antiviral activity. Some peptides exhibit direct virucidal activity, others disturb attachment of virus particles to the cell membrane surface or interfere with intracellular replication of virus. Due to limited effectiveness of commonly used drugs and emerging resistance of viruses, antiviral peptides may have the potential to be developed as putative therapeutic agents.
肽类对多种细菌、真菌和寄生虫的抗菌效率已得到广泛描述。近期对肽类的研究也证实了它们的抗病毒活性。一些肽表现出直接的杀病毒活性,另一些则干扰病毒颗粒与细胞膜表面的附着或干扰病毒的细胞内复制。由于常用药物的有效性有限以及病毒新出现的耐药性,抗病毒肽有可能被开发成为假定的治疗药物。