The Philips Institute of Oral and Craniofacial Molecular Biology, Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, USA.
J Clin Microbiol. 2012 Mar;50(3):1039-42. doi: 10.1128/JCM.06438-11. Epub 2011 Dec 21.
Oral streptococci have been associated with systemic diseases, including infective endocarditis and neutropenic bacteremia. We analyzed 58 recent oral streptococcal bloodstream isolates, and we obtained clinical and demographic data for source patients. The sodA gene was found to be a better target than the 16S-23S rRNA internal transcribed spacer for DNA sequence-based species identification. Together, Streptococcus mitis and Streptococcus oralis were significantly more likely than the 12 combined remaining species to be isolated from neutropenic patients.
口腔链球菌与包括感染性心内膜炎和中性粒细胞减少性菌血症在内的全身疾病有关。我们分析了 58 株近期口腔链球菌血流分离株，并获得了源患者的临床和人口统计学数据。 sodA 基因比 16S-23S rRNA 内部转录间隔区更适合作为 DNA 序列种属鉴定的靶标。米氏链球菌和口腔链球菌与 12 种组合剩余种属相比，更有可能从中性粒细胞减少症患者中分离出来。
