Mądry Ryszard, Strużyna Jerzy, Stachura-Kułach Aldona, Drozdz Łukasz, Bugaj Magdalena
Eastern Poland Burn Treatment and Reconstructive Center, Łęczna Hospital.
Pol Przegl Chir. 2011 Oct;83(10):541-8. doi: 10.2478/v10035-011-0086-5.
The skin is the largest organ of the human body consisting of several layers possessing different properties and performing different physiological functions. The loss of skin integrity caused by a trauma or disease may provoke acute physiological and immune disorders that may even be fatal. The following properties are primarily taken into account when choosing the appropriate burn wound dressing: support of the epithelialisation process, pain and patient discomfort reduction, and treatment costs. THE AIM OF THE STUDY was to assess the usefulness of Suprathel in the treatment of partial-thickness burns and frostbites and Lyell's syndrome and to determine the preferable time of Suprathel application to the wound.
At The Eastern Poland Burn Treatment and Reconstructive Surgery Centre, Suprathel was used in 21 patients: 11 men and 4 women with wound burns, 5 men with frostbites and 1 woman with Lyell's syndrome. Dressings were applied within 96 hours of injury.
Treatment results depended on the time of Suprathel application to the wound and on the type of injury. Among 9 partial-thickness burn patients treated within 24 h of injury, the epithelialisation time was up to 14 days in 7 patients and up to 21 days in 1 patient, and skin grafting was necessary in 1 patient. In one of the 2 partial-thickness burn patients treated on the second day after injury, the epithelialisation time was 21 days, and skin grafting was necessary in the other of these 2 patients. Among 4 partial-thickness burn patients treated on the second day after the injury, the epithelialisation time was 21 days in 2 patients and skin grafting was necessary in 2 patients. Among the 5 frostbite patients, the epithelialisation time was up to 14 days in 3 patients and up to 21 days in 2 patients. In 1 patient with Lyell's syndrome, the epithelialisation time was 21 days.
Suprathel is a good dressing that can perform the function of a temporary epidermal substitute in partial-thickness burns and frostbites and in Lyell's syndrome. The dressing should be applied within 24 hours of injury, when there is the least exudate from the wound and the wound is not infected. Therapeutic effectiveness of Suprathel decreases along with a delay of its application to the burn wound and with increasing burn depth.
皮肤是人体最大的器官,由具有不同特性并执行不同生理功能的几层组成。创伤或疾病导致的皮肤完整性丧失可能引发急性生理和免疫紊乱,甚至可能致命。选择合适的烧伤创面敷料时主要考虑以下特性:支持上皮化过程、减轻疼痛和患者不适以及治疗成本。本研究的目的是评估Suprathel在治疗浅度烧伤、冻伤和中毒性表皮坏死松解症中的有效性,并确定Suprathel应用于创面的最佳时间。
在波兰东部烧伤治疗与重建外科中心,21例患者使用了Suprathel:11例男性和4例女性有创面烧伤,5例男性有冻伤,1例女性有中毒性表皮坏死松解症。在受伤后96小时内进行敷料包扎。
治疗结果取决于Suprathel应用于创面的时间和损伤类型。在受伤后24小时内接受治疗的9例浅度烧伤患者中,7例患者的上皮化时间长达14天,1例患者长达21天,1例患者需要进行皮肤移植。在受伤后第二天接受治疗的2例浅度烧伤患者中,1例患者的上皮化时间为21天,另1例患者需要进行皮肤移植。在受伤后第二天接受治疗的4例浅度烧伤患者中,2例患者的上皮化时间为21天,2例患者需要进行皮肤移植。在5例冻伤患者中,3例患者的上皮化时间长达14天,2例患者长达21天。在1例中毒性表皮坏死松解症患者中,上皮化时间为21天。
Suprathel是一种良好的敷料,可在浅度烧伤、冻伤和中毒性表皮坏死松解症中发挥临时表皮替代物的作用。该敷料应在受伤后24小时内应用,此时创面渗出物最少且未感染。Suprathel的治疗效果会随着其应用于烧伤创面的延迟以及烧伤深度的增加而降低。