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Suprathel® 用于儿童部分厚度烧伤。

Use of Suprathel® for partial thickness burns in children.

机构信息

Department of Burns and Plastic Surgery, Central Manchester University Hospital NHS Foundation Trust, Oxford Road, Manchester M13 9WL, United Kingdom.

出版信息

Burns. 2013 Feb;39(1):136-41. doi: 10.1016/j.burns.2012.05.005. Epub 2012 Jun 13.

DOI:10.1016/j.burns.2012.05.005
PMID:22698841
Abstract

We evaluated the use of Suprathel(®), a synthetic skin substitute, for partial thickness burns in children. Thirty-three children (20 females, 13 males; mean age 29 months, range 5 months to 11 years) with burns were treated with Suprathel(®). The burns were superficial partial thickness (n=24) or mid-dermal (n=19); the median %TBSA was 4% (range 1-13%). Suprathel(®) was applied after debridement, followed by Vaseline gauze, dry gauze and crepe bandage. The outer dressings were changed every 5-10 days unless clinical problems dictated otherwise. Median healing time was 16 days (range 9-38 days). Ten patients took longer than 21 days to heal, of whom four developed hypertrophic scarring, which was strongly associated with wound infection (p<0.05). Healing time of superficial partial thickness and mid-dermal burns was not significantly different (p=0.494). Suprathel(®) is an effective skin substitute for the treatment of partial thickness burns in children. The majority of burns in children are mixed depth, and Suprathel(®) has the advantage that it may also be used to treat mid-dermal burns. It behaves like a biological dressing but is not animal derived, so is acceptable to all religious and ethnic groups. Further studies to evaluate the efficacy and cost effectiveness of Suprathel(®) compared to other dressings in children are warranted.

摘要

我们评估了合成皮肤替代物 Suprathel(®) 在儿童部分厚度烧伤中的应用。33 名(20 名女性,13 名男性;平均年龄 29 个月,范围 5 个月至 11 岁)患有烧伤的儿童接受了 Suprathel(®)治疗。烧伤为浅Ⅱ度(n=24)或深Ⅱ度(n=19);中位 TBSA 为 4%(范围 1-13%)。Suprathel(®)在清创后使用,随后使用凡士林纱布、干纱布和弹力绷带。除非临床需要,否则每 5-10 天更换一次外层敷料。中位愈合时间为 16 天(范围 9-38 天)。10 名患者的愈合时间超过 21 天,其中 4 名患者发生增生性瘢痕,这与伤口感染密切相关(p<0.05)。浅Ⅱ度和深Ⅱ度烧伤的愈合时间无显著差异(p=0.494)。Suprathel(®)是治疗儿童部分厚度烧伤的有效皮肤替代物。大多数儿童烧伤为混合深度,Suprathel(®)的优点在于它也可用于治疗深Ⅱ度烧伤。它的表现类似于生物敷料,但不是动物源性的,因此可以被所有宗教和种族接受。需要进一步研究评估 Suprathel(®)与其他敷料相比在儿童中的疗效和成本效益。

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