Takayanagi Hideo
Dept. of Psychiatry, Sapporo Medical Center NTT EC.
Gan To Kagaku Ryoho. 2011 Dec;38 Suppl 1:87-8.
There has been an increase in cancer patient referrals to our palliative care team during a cancer treatment. In order to help an end-of-life stage homecare cancer patient who becomes being depressed and the family being felt restlessness, a fine-tuned response, an early stage of revelation of the disease and treatment are essential to have a long lasting homecare environment. Based on the Basic Plan to Promote Cancer Control Programs, our hospital established a cancer consulting support center and a palliative cancer care team in June 2009, and staffed them with multidisciplinary personnel. With medical staffs involved as a team, we considered a shared decision making repeatedly in compliance with in-patient's wishes for home care. One of the problems we have experienced was that a patient would take a long time for a decision making due to the state of mental depression, even if the patient had an ability to think and evaluate oneself. For a medicinal treatment of cancer patient with the state of depression, steroid, interferon, hypertension drug, female hormone pill, anti-histamine medicine and anti-fungus agent will cause frequent side effects, but they are easy to get rid of the symptoms. It appears that 5-percent of the patients who had steroid administered 10 days ago have a tendency to have a high manifested risk in 40mg/day PURRE- DONIZORO/Japan calculated. In case of medication related depression, the symptom can be rather controlled quickly by a decrease in the amount of medication. On the other hand, there is a possibility that side effects may appear before anti-depression comes to effects in case of an ordinary depression case. And it takes 2-4 weeks for the medicine to be effective. Therefore, amid the cancer patient is being in the state of depression, a decision to transfer the patient for home care environment should be delayed. This is why we ought to investigate it as one of the problems in palliative care. In conclusion, due to a patient's inability to make own decision, or for a home care period to be not shortened, or we fail to make a right timing to for sending the patient to home, a careful daily observation and a fine-tuned response are desired for a sign of depression with the cancer patient.
在癌症治疗期间,转介至我们姑息治疗团队的癌症患者有所增加。为帮助处于临终阶段、出现抑郁情绪且家人感到不安的居家癌症患者,做出微调的应对措施、在疾病和治疗的早期阶段予以告知,对于营造持久的居家护理环境至关重要。根据《促进癌症控制计划基本方案》,我院于2009年6月设立了癌症咨询支持中心和姑息性癌症护理团队,并配备了多学科人员。医护人员作为一个团队参与其中,我们根据住院患者对居家护理的意愿反复考虑共同决策。我们遇到的问题之一是,即使患者有思考和自我评估的能力,但由于精神抑郁状态,患者做出决策可能需要很长时间。对于处于抑郁状态的癌症患者进行药物治疗时,类固醇、干扰素、高血压药物、女性激素药丸、抗组胺药和抗真菌剂会频繁引发副作用,但这些副作用很容易消除症状。似乎在10天前接受类固醇治疗的患者中,按日本计算的40mg/天的PURRE - DONIZORO,有5%的患者有高显化风险。在药物相关性抑郁的情况下,通过减少药物剂量,症状可以相当迅速地得到控制。另一方面,在普通抑郁症病例中,有可能在抗抑郁药起效之前就出现副作用。而且药物需要2至4周才能起效。因此,在癌症患者处于抑郁状态时,将患者转至居家护理环境的决定应推迟。这就是为什么我们应该将其作为姑息治疗中的一个问题来进行调查。总之,由于患者无法自行做出决定,或居家护理期未缩短,或我们未能把握将患者送回家的正确时机,对于癌症患者的抑郁迹象,需要进行仔细的日常观察并做出微调的应对措施。