Panasiuk N N, Mukhin N A, Varshavskiĭ V A, Maksimov N A, Nikolaev A Iu, Poliantseva L R, Balkarov I M, Golov K G, Antonov M V, Aleksandrovskaia T N
Ter Arkh. 1990;62(6):99-103.
Based on studying the data obtained during examination of patients with psoriasis combined with the urinary syndrome possible varieties of psoriatic nephropathy, namely chronic glomerulonephritis (CGN) and amyloidosis were distinguished. CGN combined with psoriasis was mainly represented by latent glomerulonephritis (GN) and morphologically, it was mostly represented by the mesangio-proliferative variant, with IgA and C3 being fixed on the basal membrane of the capillaries and in the mesangium. The clinicomorphological feature of that form of psoriatic GN is combination of the signs of both associated CGN and hyperuricemia and IgA-nephritis. Special emphasis is laid on the diagnosis of rapid-progressing GN which is of paramount importance for institution of early etiopathogenetic therapy. Amyloidosis associated with psoriasis is characterized by the signs of acquired disease (AA-amyloidosis) and does not differ in its course from amyloidosis coupled with other diseases.
通过研究银屑病合并泌尿系统综合征患者检查期间获得的数据,区分出了银屑病肾病的可能类型,即慢性肾小球肾炎(CGN)和淀粉样变性。银屑病合并的CGN主要表现为隐匿性肾小球肾炎(GN),形态学上大多表现为系膜增生性变体,IgA和C3固定在毛细血管基底膜和系膜中。这种银屑病性GN的临床形态学特征是相关CGN、高尿酸血症和IgA肾病的体征相结合。特别强调快速进展性GN的诊断,这对早期病因治疗的实施至关重要。与银屑病相关的淀粉样变性以获得性疾病(AA淀粉样变性)的体征为特征,其病程与其他疾病合并的淀粉样变性无差异。