Johnson Kirstin C, Mackin Andrew
Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, USA.
J Am Anim Hosp Assoc. 2012 Jan-Feb;48(1):12-7. doi: 10.5326/JAAHA-MS-5744. Epub 2011 Dec 21.
Immune-mediated polyarthritis (IMPA) is a common disease process in the dog.(1) The immune-mediated polyarthropathies are divided into two major categories: erosive (or deforming) and nonerosive (or nondeforming). Understanding the pathophysiology of the immune attack on affected joints is paramount in choosing the most effective therapy for managing canine IMPA. This review article is the first of a two-part series and focuses on the pathophysiology of IMPA. The second article in this series, to be published in the March/April 2012 issue, concentrates on the diagnosis and treatment of immune-mediated polyarthritis.
免疫介导性多关节炎（IMPA）是犬类常见的疾病过程。（1）免疫介导性多关节病分为两大类：侵蚀性（或变形性）和非侵蚀性（或非变形性）。了解对受影响关节的免疫攻击的病理生理学对于选择治疗犬类IMPA的最有效疗法至关重要。这篇综述文章是两部分系列文章中的第一篇，重点关注IMPA的病理生理学。本系列的第二篇文章将于2012年3月/4月期发表，重点关注免疫介导性多关节炎的诊断和治疗。
