血清C反应蛋白作为犬II型免疫介导性多关节炎炎症活动早期标志物的应用：病例报告
Use of serum C-reactive protein as an early marker of inflammatory activity in canine type II immune-mediated polyarthritis: case report.
作者信息
Kjelgaard-Hansen Mads, Jensen Asger Lundorff, Houser Geoffrey A, Jessen Lisbeth Rem, Kristensen Annemarie T
机构信息
Central Laboratory, Department of Small Animal Clinical Sciences, The Royal Veterinary and Agricultural University, 3 Gronnegaardsvej, DK-1870 Frederiksberg, Denmark.
出版信息
Acta Vet Scand. 2006 Jun 21;48(1):9. doi: 10.1186/1751-0147-48-9.
BACKGROUND
Monitoring systemic inflammatory activity during steroid therapy of canine immune-mediated polyarthritis (IMPA) is difficult and mainly relies on clinical signs.
CASE PRESENTATION
Canine serum C-reactive protein (CRP) was measured serially and blinded during a 27-week follow-up period of a case of Anaplasma phagocytophilia induced type II immune-mediated polyarthritis.
CONCLUSION
WBC was, as expected, observed not to reflect the inflammatory activity during steroid treatment in a clinical useful manner, whereas, CRP is suggested a valuable unbiased marker of inflammatory activity during steroid treatment in this case.
背景
在犬免疫介导性多关节炎（IMPA）的类固醇治疗期间监测全身炎症活动很困难，主要依赖临床症状。
病例报告
在一例嗜吞噬细胞无形体诱导的II型免疫介导性多关节炎病例的27周随访期间，对犬血清C反应蛋白（CRP）进行了连续且盲法检测。
结论
正如预期的那样，观察到白细胞在类固醇治疗期间不能以临床有用的方式反映炎症活动，而在该病例中，CRP被认为是类固醇治疗期间炎症活动的一个有价值的无偏倚标志物。
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