犬免疫介导性多关节炎：加拿大西部83例病例的临床及实验室检查结果（1991 - 2001年）
Canine immune-mediated polyarthritis: clinical and laboratory findings in 83 cases in western Canada (1991-2001).
作者信息
Stull Jason W, Evason Michelle, Carr Anthony P, Waldner Cheryl
机构信息
Departments of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan.
出版信息
Can Vet J. 2008 Dec;49(12):1195-203.
A hospital-based, case-control study was used to describe clinical and laboratory findings in 83 dogs diagnosed with noninfectious, nonerosive, immune-mediated polyarthritis (IMPA) in western Canada. Case medical records were reviewed. Cases were analyzed as total IMPA cases and as subgroups [breed, systemic lupus erythematosus (SLE), reactive, and idiopathic] and compared with the general canine hospital population. Dogs with IMPA differed in age (P = 0.004) and weight (P = 0.01) from other hospital admissions. Idiopathic IMPA cases were older (4-10 y; P < 0.05), compared with the general canine hospital population, and their common laboratory abnormalities included the following: leukocytosis, nonregenerative anemia, increased alkaline phosphatase, and hypoalbuminemia. The SLE cases were seen more often in summer and fall (P = 0.04), raising concern of an undiagnosed etiologic agent. The hock joint appeared to be the most reliable for diagnosis of IMPA, and arthrocentesis of both hock joints may aid in case identification.
一项基于医院的病例对照研究用于描述加拿大西部83只被诊断为非感染性、非侵蚀性、免疫介导性多关节炎（IMPA）的犬的临床和实验室检查结果。回顾了病例医疗记录。病例被分析为总的IMPA病例以及亚组[品种、系统性红斑狼疮（SLE）、反应性和特发性]，并与普通犬科医院的犬群进行比较。患有IMPA的犬在年龄（P = 0.004）和体重（P = 0.01）方面与其他入院犬不同。与普通犬科医院的犬群相比，特发性IMPA病例年龄更大（4 - 10岁；P < 0.05），其常见的实验室异常包括：白细胞增多、非再生性贫血、碱性磷酸酶升高和低白蛋白血症。SLE病例在夏季和秋季更为常见（P = 0.04），这引发了对一种未确诊病原体的担忧。跗关节似乎是诊断IMPA最可靠的部位，双侧跗关节穿刺术可能有助于病例识别。
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