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在使用芬太尼和咪达唑仑进行清醒镇静的颞下颌关节强直患者中进行清醒盲探鼻气管插管。

Awake Blind Nasotracheal Intubation in Temporomandibular Joint Ankylosis Patients under Conscious Sedation Using Fentanyl and Midazolam.

作者信息

Dhasmana Satish, Singh Vibha, Pal U S

出版信息

J Maxillofac Oral Surg. 2010 Dec;9(4):377-81. doi: 10.1007/s12663-010-0159-8. Epub 2011 Mar 17.

Abstract

BACKGROUND AND OBJECTIVES

Intubating a patient with temporomandibular joint ankylosis is always a challenge particularly when fibreoptic laryngoscope is not available. Awake blind nasotracheal intubation requires sufficient patient co operation and comfort. Presently available short-acting analgesics and amnesics are excellent choices for this exercise.

STUDY DESIGN

This prospective randomized double blind study was designed to determine an appropriate dosage of fentanyl for awake blind nasotracheal intubation. We compared two different dosage of fentanyl. Eighty patients were randomly assigned to receive midazolam 0.05 mg/kg and fentanyl 2μg/kg in bolus (group I), or midazolam 0.05 mg/kg, fentanyl 3μg/kg in bolus (group II).

RESULTS

Both dosage regimen ensured patient comfort and sedation. Patients in group II were more calm and sedated as compared to group I. Hemodynamics was also more stable in group II.

CONCLUSION

For awake blind nasotracheal intubation, we therefore recommend midazolam 0.05mg/kg plus fentanyl 3μg/kg in bolus.

摘要

背景与目的

给颞下颌关节强直患者插管始终是一项挑战,尤其是在没有纤维喉镜的情况下。清醒盲探经鼻气管插管需要患者充分配合且保持舒适。目前可用的短效镇痛药和遗忘药是此项操作的理想选择。

研究设计

本前瞻性随机双盲研究旨在确定清醒盲探经鼻气管插管时芬太尼的合适剂量。我们比较了两种不同剂量的芬太尼。80例患者被随机分为两组,一组静脉推注咪达唑仑0.05mg/kg和芬太尼2μg/kg(第一组),另一组静脉推注咪达唑仑0.05mg/kg和芬太尼3μg/kg(第二组)。

结果

两种给药方案均确保了患者的舒适度和镇静效果。与第一组相比,第二组患者更平静、镇静效果更好。第二组的血流动力学也更稳定。

结论

因此,对于清醒盲探经鼻气管插管,我们推荐静脉推注咪达唑仑0.05mg/kg加芬太尼3μg/kg。

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