Department of Otolaryngology, Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2011 Dec;74(12):570-3. doi: 10.1016/j.jcma.2011.09.012. Epub 2011 Oct 10.
Adenocarcinoma of the prostate (CAP) is a rare diagnosis in men younger than 50 years of age; this age group accounts for less than 0.1% of all patients with prostatic cancer. Left supraclavicular lymphadenopathy (LSCL) as the presenting symptom of metastatic CAP is even rarer. No cases of CAP presenting as LSCL in men younger than 45 years have been reported in the literature. Here we report a 42-year-old male with the uncommon presentation of CAP as LSCL. In adult males with persistent LSCL, even if younger than 45 years, measurement of serum prostate specific antigen is warranted at the time of initial presentation, and the lymph node biopsy should be subsequently stained for prostate specific antigen immunohistochemically. These examinations are crucial to establish a definitive diagnosis of CAP and, in turn, to institute appropriate management and achieve the best possible outcome.
前列腺腺癌（CAP）在 50 岁以下男性中罕见诊断；这一年龄组不到所有前列腺癌患者的 0.1%。以左侧锁骨上淋巴结病（LSCL）为表现的转移性 CAP 更为罕见。文献中尚无报道称 45 岁以下男性 CAP 表现为 LSCL。在此，我们报告了一例 42 岁男性以 LSCL 为表现的罕见 CAP。对于持续性 LSCL 的成年男性，即使年龄小于 45 岁，在初次就诊时也应测量血清前列腺特异性抗原，如果有必要，随后应进行淋巴结活检，行前列腺特异性抗原免疫组织化学染色。这些检查对于明确 CAP 的诊断至关重要，进而进行适当的管理并获得尽可能好的结果。
