Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Free Radic Biol Med. 2012 Feb 1;52(3):705-715. doi: 10.1016/j.freeradbiomed.2011.11.027. Epub 2011 Dec 16.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Authors. Since learning of potential discrepancies between the raw data from the animal pulmonary physiology laboratory at Duke that were used to calculate the in vivo pulmonary mechanics and the re-exported machine-generated raw data, some studies published elsewhere have been replicated successfully. However it is not possible to replicate this study as the NQO1-deficient mice on the C57BL/6 background are no longer available from the NCI. The authors recognize that previous work to identify differences in alveolar size can vary dependent on background strain when comparing inbred mouse strains (Soutiere SE et al Resp Physiol Neurobiol 2004;140(3)183–91 doi: 10.1016/j.resp.2004.02.003). Because of the prolonged period of time required to successfully backcross NQO1-deficient animals onto C57BL/6J background and the time required to repeat studies presented in this manuscript the authors think it does not seem feasible to conduct replicate studies in a reasonable timeline. Therefore, the most appropriate course of action is to retract the report as it is the authors' goal to maintain accuracy of the scientific record to the best of their ability. The authors offer sincere apologies to the scientific community.
请参阅爱思唯尔关于文章撤回的政策（https://www.elsevier.com/about/our-business/policies/article-withdrawal）。应作者要求撤回本文。自杜克大学动物肺部生理学实验室用于计算体内肺部力学的原始数据与重新导出的机器生成原始数据之间存在潜在差异以来，已成功复制了其他地方发表的一些研究。但是，由于 NCI 不再提供 C57BL/6 背景下的 NQO1 缺陷型小鼠，因此无法复制这项研究。作者认识到，当比较近交小鼠品系时，以前识别肺泡大小差异的工作可能因背景品系而异（Soutiere SE 等人，Resp Physiol Neurobiol 2004；140（3）183-91，doi：10.1016/j.resp.2004.02.003）。由于将 NQO1 缺陷型动物成功回交至 C57BL/6J 背景所需的时间较长，以及重复本文中提出的研究所需的时间，作者认为在合理的时间内进行重复研究似乎是不可行的。因此，最合适的做法是撤回报告，因为作者的目标是尽最大能力维护科学记录的准确性。作者向科学界表示诚挚的歉意。
