[奇异变形杆菌素和热原对小鼠流感病毒抗原体液反应的刺激作用]
[The prodigiozan and pyrogenal stimulation of the humoral response to influenza virus antigens in mice].
作者信息
Khromov I S, Isaeva E I
出版信息
Vopr Virusol. 1990 May-Jun;35(3):193-4.
PMID:2219848
Abstract
The adjuvant properties of prodigiosan and pyrogenal, lipopolysaccharides of medical importance, were studied. Prodigiosan inoculated to mice together with influenza virus was found, on the one hand, to increase 10-fold the titer of specific antibodies and, on the other, to allow to reduce the antigen dose 50-fold or more. No adjuvant properties of pyrogenal were observed under the experimental conditions.
摘要
对医学上重要的脂多糖灵菌红素和热原质的佐剂特性进行了研究。一方面发现，将灵菌红素与流感病毒一起接种给小鼠，可使特异性抗体滴度提高10倍，另一方面可使抗原剂量减少50倍或更多。在实验条件下未观察到热原质的佐剂特性。
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