Reddy Indukooru Subrayalu, Swain Meenakshi, Gowrishankar Swarnalata, Murthy Dronamraju Butchi Narayana
Department of Dermatology, Apollo Hospitals, Hyderabad, India.
Indian J Dermatol Venereol Leprol. 2012 Jan-Feb;78(1):89-92. doi: 10.4103/0378-6323.90954.
Extramammary Paget's disease (EMPD) is an uncommon malignancy that is most commonly seen in the vulval area in postmenopausal women. Pruritus is the predominant symptom. The clinical presentation can be so nonspecific that it can be misdiagnosed as an inflammatory or infective condition. We report an elderly male patient with EMPD over the pubic area, which remained asymptomatic for 5 years; he presented with severe low backache of 5 months' duration. Skin biopsy and immunohistochemistry showed the typical epidermal changes and deep dermal invasion. Positron emission tomography scan revealed involvement of regional lymph nodes as well as extensive skeletal metastases.
乳房外佩吉特病（EMPD）是一种罕见的恶性肿瘤，最常见于绝经后女性的外阴区域。瘙痒是主要症状。其临床表现可能非常不具有特异性，以至于可能被误诊为炎症或感染性疾病。我们报告一名老年男性患者，其耻骨区域患有EMPD，5年来一直无症状；他出现了持续5个月的严重腰痛。皮肤活检和免疫组化显示典型的表皮变化和真皮深层浸润。正电子发射断层扫描显示区域淋巴结受累以及广泛的骨骼转移。
