Suh Eunyoung Eunice
College of Nursing, Seoul National University, South Korea.
Oncol Nurs Forum. 2012 Jan;39(1):E1-9. doi: 10.1188/12.ONF.E1-E9.
PURPOSE/OBJECTIVES: To evaluate the effects of pericardium 6 (P6) acupressure and nurse-provided counseling on chemotherapy-induced nausea and vomiting (CINV) in patients with breast cancer.
Randomized, controlled trial.
A university cancer center in Seoul, South Korea.
120 women who were beginning their second cycle of adjuvant chemotherapy after definitive surgery for breast cancer and who had more than mild levels of nausea and vomiting with the first cycle of chemotherapy.
Participants were assigned randomly into four groups: control (placebo on SI3), counseling only, P6 acupressure only, and P6 acupressure plus nurse-provided counseling. The experiences of upper-gastrointestinal distress were measured by the Rhodes Index of Nausea, Vomiting, and Retching for acute (day 1) and delayed (day 2 to day 5) CINV.
Nausea, retching, vomiting, P6 acupressure, and counseling.
No significant differences were found in the demographic and disease-related variables among the four groups. The levels of CINV were significantly different among the groups from day 2 to day 5. The CINV differences were attributed mainly to the difference between the control group and the group with P6 acupressure plus nurse-provided counseling. The effects of acupressure were proven from day 2 to day 5, and the effects of nurse-provided counseling were proven on day 4 and were close to significance level on day 5.
Synergic effects of P6 acupressure with nurse-provided counseling appeared to be effective in reducing CINV in patients with breast cancer.
P6 acupressure combined with counseling by nurses is a safe and easy-to-apply tool in CINV management in practice.
目的/目标：评估心包经6穴（P6）指压法及护士提供的咨询服务对乳腺癌患者化疗所致恶心和呕吐（CINV）的影响。
随机对照试验。
韩国首尔的一所大学癌症中心。
120名女性，她们在乳腺癌根治性手术后开始辅助化疗的第二个周期，且在第一个化疗周期中有中度以上的恶心和呕吐症状。
参与者被随机分为四组：对照组（在小肠经3穴进行安慰剂治疗）、仅接受咨询组、仅进行P6指压法组、P6指压法加护士提供咨询组。通过恶心、呕吐及干呕的罗德指数来测量急性（第1天）和延迟性（第2天至第5天）CINV的上消化道不适情况。
恶心、干呕、呕吐、P6指压法及咨询服务。
四组在人口统计学和疾病相关变量方面未发现显著差异。从第2天到第5天，各组间CINV水平存在显著差异。CINV的差异主要归因于对照组与P6指压法加护士提供咨询组之间的差异。指压法的效果在第2天到第5天得到证实，护士提供咨询服务的效果在第4天得到证实，在第5天接近显著水平。
P6指压法与护士提供的咨询服务协同作用似乎对降低乳腺癌患者的CINV有效。
P6指压法与护士咨询相结合是实践中管理CINV的一种安全且易于应用的工具。
