Neuroscience and Aphasia Research Unit, University of Manchester, Manchester, UK.
Arch Phys Med Rehabil. 2012 Jan;93(1 Suppl):S53-60. doi: 10.1016/j.apmr.2011.07.205.
Anomia refers to difficulties retrieving words and is 1 of the most common symptoms of aphasia and hence often the target of therapy. The principal aim of the present study was to explore, for the first time, whether it is possible to predict the responsiveness of individual words to naming therapy from the psycholinguistic properties of those words and from the length of the phonemic cue required to name them. The relationship between this form of cueing and the outcome of naming therapy is of particular interest given that cueing is an established research and clinical tool within aphasiology, and is commonly used to probe naming performance.
By amalgamating data from 3 previous studies, we were able to analyze data from 22 participants with chronic aphasia, yielding cueing and therapy data for 1080 target words. Cross-session changes in cueing and naming accuracy were collated for 298 target words.
The results demonstrated that items which were accurately named after therapy (both at 1 wk and 5 wk later) required a significantly shorter phonemic cue to prompt correct naming in assessments prior to therapy. Imageability was a significant predictor of the required cue level, whereas word age of acquisition and word frequency were not. Highly imageable words required less cueing and were more likely to be accurately named posttherapy. A novel analysis of cross-session accuracy revealed that, even though the required cue length reduced across the first 6 of 10 therapy sessions, the relationship between the required cue length and final posttherapy accuracy was present throughout therapy.
The findings are discussed in the context of their clinical implications for intervention, specifically for therapies that focus on accurate production of specific word targets. Themes for future related research are also considered.
命名障碍是指在提取单词时出现困难，它是失语症最常见的症状之一，因此往往是治疗的目标。本研究的主要目的是首次探索是否可以根据单词的心理语言学特性以及命名它们所需的音素提示的长度，预测个别单词对命名治疗的反应性。鉴于提示是失语症学中一种既定的研究和临床工具，并且常用于探测命名表现，因此这种提示形式与命名治疗结果之间的关系特别有趣。
通过合并 3 项先前研究的数据，我们能够分析 22 名慢性失语症患者的数据，得出 1080 个目标词的提示和治疗数据。对 298 个目标词的跨会话提示和命名准确性变化进行了整理。
结果表明，治疗后（1 周和 5 周后）准确命名的项目在治疗前的评估中需要更短的音素提示才能正确命名。可想象性是所需提示水平的重要预测指标，而习得年龄和词频则不是。高度可想象的单词需要较少的提示，并且更有可能在治疗后被准确命名。对跨会话准确性的新分析表明，尽管在 10 次治疗中的前 6 次中所需的提示长度有所减少，但提示长度与治疗后最终准确性之间的关系在整个治疗过程中均存在。
这些发现将根据其对干预的临床意义进行讨论，特别是对于专注于特定单词目标准确产生的治疗方法。还考虑了与未来相关研究的主题。
