使用多能干细胞进行针对神经疾病的个性化细胞治疗。
The use of pluripotent stem cell for personalized cell therapies against neurological disorders.
作者信息
Ha Hye-Yeong, Jang Si-Hyong, Jung Ji-Won
机构信息
Division of Intractable Diseases, Center for Biomedical Science, Korea National Institute of Health, Cheongwon-gun, Chungbuk 363-700, Republic of Korea.
出版信息
J Biomed Biotechnol. 2011;2011:520816. doi: 10.1155/2011/520816. Epub 2011 Dec 13.
Although there are a number of weaknesses for clinical use, pluripotent stem cells are valuable sources for patient-specific cell therapies against various diseases. Backed-up by a huge number of basic researches, neuronal differentiation mechanism is well established and pluripotent stem cell therapies against neurological disorders are getting closer to clinical application. However, there are increasing needs for standardization of the sourcing pluripotent stem cells by establishing stem cell registries and banking. Global harmonization will accelerate practical use of personalized therapies using pluripotent stem cells.
尽管多能干细胞在临床应用上存在一些不足，但它是针对各种疾病进行患者特异性细胞治疗的宝贵来源。在大量基础研究的支持下，神经元分化机制已得到充分确立，针对神经疾病的多能干细胞治疗正日益接近临床应用。然而，通过建立干细胞登记处和库来实现多能干细胞来源的标准化的需求也日益增加。全球协调将加速多能干细胞个性化治疗的实际应用。
Zotero 插件