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介入心脏病学家中的脑肿瘤:值得警惕吗?来自两个城市的 4 个新病例报告及文献复习。

Brain tumours among interventional cardiologists: a cause for alarm? Report of four new cases from two cities and a review of the literature.

机构信息

Interventional Cardiology, Rambam Medical Center, Bruce Rappaport Faculty of Medicine, the Technion, Israel Institute of Technology, Haifa, Israel.

出版信息

EuroIntervention. 2012 Jan;7(9):1081-6. doi: 10.4244/EIJV7I9A172.

DOI:10.4244/EIJV7I9A172
PMID:22207231
Abstract

AIMS

Interventional cardiologists who work in cardiac catheterisation laboratories are exposed to low doses of ionising radiation that could pose a health hazard. DNA damage is considered to be the main initiating event by which radiation damage to cells results in development of cancer.

METHODS AND RESULTS

We report on four interventional cardiologists, all with brain malignancies in the left hemisphere. In a literature search, we found five additional cases and thus present data on six interventional cardiologist and three interventional radiologists who were diagnosed with brain tumours. All worked for prolonged periods with exposure to ionising radiation in the catheterisation laboratory.

CONCLUSIONS

In interventional cardiologists and radiologists, the left side of the head is known to be more exposed to radiation than the right. A connection to occupational radiation exposure is biologically plausible, but risk assessment is difficult due to the small population of interventional cardiologists and the low incidence of these tumours. This may be a chance occurrence, but the cause may also be radiation exposure. Scientific study further delineating occupational risks is essential. Since interventional cardiologists have the highest radiation exposure among health professionals, major awareness of radiation safety and training in radiological protection are essential and imperative, and should be used in every procedure.

摘要

目的

在心脏导管实验室工作的介入心脏病学家会接触到低剂量的电离辐射,这可能会对健康造成危害。DNA 损伤被认为是辐射对细胞造成损伤导致癌症发展的主要起始事件。

方法和结果

我们报告了四位介入心脏病学家,他们都患有左半球的脑恶性肿瘤。在文献检索中,我们发现了另外五例病例,因此我们提供了六名介入心脏病学家和三名介入放射学家的脑肿瘤诊断数据。所有这些医生都在导管实验室工作了很长时间,暴露在电离辐射下。

结论

在介入心脏病学家和放射科医生中,已知头部的左侧比右侧更容易受到辐射。与职业辐射暴露的联系在生物学上是合理的,但由于介入心脏病学家的人数较少,而且这些肿瘤的发病率较低,因此风险评估很困难。这可能是偶然发生的,但原因也可能是辐射暴露。进一步阐明职业风险的科学研究至关重要。由于介入心脏病学家是所有医疗保健专业人员中受到辐射暴露最高的人群,因此对辐射安全的高度认识和放射防护培训是必不可少的,并且应该在每个程序中使用。

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Brain tumours among interventional cardiologists: a cause for alarm? Report of four new cases from two cities and a review of the literature.介入心脏病学家中的脑肿瘤:值得警惕吗?来自两个城市的 4 个新病例报告及文献复习。
EuroIntervention. 2012 Jan;7(9):1081-6. doi: 10.4244/EIJV7I9A172.
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