Doğan Nurhan, Toprak Dilek, Demir Serap
Department of Biostatistical and Medical Informatics, Afyon Kocatepe University, Afyonkarahisar-Turkey.
Anadolu Kardiyol Derg. 2012 Feb;12(1):47-52. doi: 10.5152/akd.2012.009. Epub 2012 Jan 4.
Hypertension is a major public health problem worldwide with increasing prevalence. The purpose of this study was to examine the prevalence of hypertension and related risk factors among adult population in Afyonkarahisar region.
In this cross-sectional research, regarding the population distribution totally 2035 subjects, randomly selected from 75 different parts of our city, both the urban and the rural areas, were included in this epidemiologic research. After the administration of a questionnaire to the subjects, blood samples were taken and physical examinations were performed. Socio-demographic features, diabetes mellitus (DM), hypertension, family history of hypertension, coronary heart disease (CHD), smoking, and number of births were evaluated as possible risk factors for hypertension. Statistical analysis was performed using Student's t-test, Chi-square test and binary logistic regression analysis.
The overall prevalence of hypertension was 24.2% (31.3% in women, 14.1% in men, p<0.001). Its prevalence increased with age (from 2.2% to 50.4%, p<0.001). Age, gender, DM, family history of hypertension, body mass index (BMI), CHD and income levels were significant risk factors. Diabetic patients had 2.35 times (95%CI 1.70-3.25: p<0.0001) more risk, people who had positive family history 2.23 times (95%CI 1.62-3.07: p<0.0001) more risk and those with high BMI 2.15 times (95%CI 1.66-2.78: p<0.0001) more risk to develop HT than who did not have these factors. In addition, women have 2.74 times (95%CI 2.08-3.62: p<0.0001), more risk than men for HT. We determined CHD and low income as other risk factors for HT (OR=2.32, 95%CI 1.48-3.64: p<0.0001) and OR=1.47, 95%CI 1.08-2.02: p=0.016 respectively).
Hypertension is an important health problem in our region. We think that it is possible to reduce the hypertension prevalence with lifestyle changes and educating people, regarding the risk factors.
高血压是全球范围内一个主要的公共卫生问题,其患病率不断上升。本研究的目的是调查阿菲永卡拉希萨尔地区成年人群中高血压的患病率及相关危险因素。
在这项横断面研究中,根据人口分布,从我们城市的75个不同地区(包括城市和农村)随机选取了2035名受试者纳入这项流行病学研究。在对受试者进行问卷调查后,采集血样并进行体格检查。将社会人口学特征、糖尿病(DM)、高血压、高血压家族史、冠心病(CHD)、吸烟和生育次数评估为高血压的可能危险因素。采用学生t检验、卡方检验和二元逻辑回归分析进行统计分析。
高血压的总体患病率为24.2%(女性为31.3%,男性为14.1%,p<0.001)。其患病率随年龄增长而增加(从2.2%增至50.4%,p<0.001)。年龄、性别、糖尿病、高血压家族史、体重指数(BMI)、冠心病和收入水平是显著的危险因素。糖尿病患者发生高血压的风险是无这些因素者的2.35倍(95%可信区间1.70 - 3.25:p<0.0001),有高血压家族史者是2.23倍(95%可信区间1.62 - 3.07:p<0.0001),BMI高者是2.15倍(95%可信区间1.66 - 2.78:p<0.0001)。此外,女性发生高血压的风险是男性的2.74倍(95%可信区间2.08 - 3.62:p<0.0001)。我们确定冠心病和低收入是高血压的其他危险因素(OR = 2.32,95%可信区间1.48 - 3.64:p<0.0001)和OR = 1.47,95%可信区间1.08 - 2.02:p = 0.016)。
高血压是我们地区一个重要的健康问题。我们认为通过改变生活方式和对人们进行危险因素教育,有可能降低高血压的患病率。