Department of Medicine, Division of Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sleep. 2012 Jan 1;35(1):149-58. doi: 10.5665/sleep.1606.
To evaluate reliability of single objective tests in assessing sleepiness.
Subjects who completed polysomnography underwent a 4-nap multiple sleep latency test (MSLT) the following day. Prior to each nap opportunity on MSLT, subjects performed the psychomotor vigilance test (PVT) and divided attention driving task (DADT). Results of single versus multiple test administrations were compared using the intraclass correlation coefficient (ICC) and adjusted for test administration order effects to explore time of day effects. Measures were explored as continuous and binary (i.e., impaired or not impaired).
Community-based sample evaluated at a tertiary, university-based sleep center.
372 adult commercial vehicle operators oversampled for increased obstructive sleep apnea risk.
N/A.
AS CONTINUOUS MEASURES, ICC WERE AS FOLLOWS: MSLT 0.45, PVT median response time 0.69, PVT number of lapses 0.51, 10-min DADT tracking error 0.87, 20-min DADT tracking error 0.90. Based on binary outcomes, ICC were: MSLT 0.63, PVT number of lapses 0.85, 10-min DADT 0.95, 20-min DADT 0.96. Statistically significant time of day effects were seen in both the MSLT and PVT but not the DADT. Correlation between ESS and different objective tests was strongest for MSLT, range [-0.270 to -0.195] and persisted across all time points.
Single DADT and PVT administrations are reliable measures of sleepiness. A single MSLT administration can reasonably discriminate individuals with MSL < 8 minutes. These results support the use of a single administration of some objective tests of sleepiness when performed under controlled conditions in routine clinical care.
评估单一客观测试评估嗜睡的可靠性。
完成多导睡眠图的受试者次日进行 4 次小睡多次睡眠潜伏期测试（MSLT）。在 MSLT 的每次小睡机会之前，受试者进行了精神运动警觉测试（PVT）和注意分散驾驶任务（DADT）。使用组内相关系数（ICC）比较单次和多次测试结果，并调整测试顺序效应以探索时间效应。测量结果以连续和二分类（即受损或未受损）呈现。
在三级、以大学为基础的睡眠中心评估的社区样本。
372 名成年商用车辆驾驶员，样本量增加以增加阻塞性睡眠呼吸暂停风险。
无。
作为连续测量，ICC 如下：MSLT 为 0.45，PVT 中位反应时间为 0.69，PVT 失误次数为 0.51，10 分钟 DADT 跟踪误差为 0.87，20 分钟 DADT 跟踪误差为 0.90。基于二分类结果，ICC 为：MSLT 为 0.63，PVT 失误次数为 0.85，10 分钟 DADT 为 0.95，20 分钟 DADT 为 0.96。MSLT 和 PVT 均显示出明显的时间效应，但 DADT 没有。ESS 与不同客观测试之间的相关性最强的是 MSLT，范围为[-0.270 至-0.195]，并在所有时间点持续存在。
单次 DADT 和 PVT 测试是评估嗜睡的可靠指标。单次 MSLT 测试可合理区分 MSL<8 分钟的个体。这些结果支持在常规临床护理中在受控条件下进行单次客观嗜睡测试时使用。
