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美国食源性疾病导致的健康损失的经济负担。

Economic burden from health losses due to foodborne illness in the United States.

机构信息

The Ohio State University, Columbus, Ohio 43210, USA.

出版信息

J Food Prot. 2012 Jan;75(1):123-31. doi: 10.4315/0362-028X.JFP-11-058.

Abstract

The Centers for Disease Control and Prevention (CDC) recently revised their estimates for the annual number of foodborne illnesses; 48 million Americans suffer from domestically acquired foodborne illness associated with 31 identified pathogens and a broad category of unspecified agents. Consequently, economic studies based on the previous estimates are now obsolete. This study was conducted to provide improved and updated estimates of the cost of foodborne illness by adding a replication of the 2011 CDC model to existing cost-of-illness models. The basic cost-of-illness model includes economic estimates for medical costs, productivity losses, and illness-related mortality (based on hedonic value-of-statistical-life studies). The enhanced cost-of-illness model replaces the productivity loss estimates with a more inclusive pain, suffering, and functional disability measure based on monetized quality-adjusted life year estimates. Costs are estimated for each pathogen and a broader class of unknown pathogens. The addition of updated cost data and improvements to methodology enhanced the performance of each existing economic model. Uncertainty in these models was characterized using Monte Carlo simulations in @Risk version 5.5. With this model, the average cost per case of foodborne illness was $1,626 (90% credible interval [CI], $607 to $3,073) for the enhanced cost-of-illness model and $1,068 (90% CI, $683 to $1,646) for the basic model. The resulting aggregated annual cost of illness was $77.7 billion (90% CI, $28.6 to $144.6 billion) and $51.0 billion (90% CI, $31.2 to $76.1 billion) for the enhanced and basic models, respectively.

摘要

疾病预防控制中心(CDC)最近修订了其对每年食源性疾病数量的估计;4800 万美国人遭受与 31 种已确定病原体和广泛的未指明病原体有关的食源性疾病。因此,基于先前估计的经济研究现在已经过时。本研究旨在通过添加对现有疾病成本模型的 2011 年 CDC 模型的复制,提供食源性疾病成本的改进和更新估计。基本疾病成本模型包括医疗成本、生产力损失和与疾病相关的死亡率的经济估计(基于享乐价值统计生命研究)。增强的疾病成本模型用基于货币化的调整生命年估计的更全面的疼痛、痛苦和功能障碍衡量标准替代生产力损失估计。为每个病原体和更广泛的未知病原体类别估计成本。更新成本数据的增加和方法的改进提高了每个现有经济模型的性能。使用 @Risk 版本 5.5 中的蒙特卡罗模拟来描述这些模型的不确定性。使用该模型,食源性疾病的每例平均成本为增强型疾病成本模型的 1626 美元(90%可信区间[CI],607 美元至 3073 美元)和基本模型的 1068 美元(90%CI,683 美元至 1646 美元)。由此产生的年度疾病总费用分别为 777 亿美元(90%CI,286 亿美元至 1446 亿美元)和 510 亿美元(90%CI,312 亿美元至 761 亿美元),增强模型和基本模型分别为 77.7 亿美元(90%CI,28.6 亿美元至 144.6 亿美元)和 51.0 亿美元(90%CI,31.2 亿美元至 76.1 亿美元)。

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