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编码乙型肝炎表面抗原中蛋白的重组痘苗病毒的启动效应

Priming effect of recombinant vaccinia virus coding for the middle hepatitis B surface antigen.

作者信息

Hamsíková E, Závadová H, Kutinová L, Ludvíková V, Krchnák V, Némecková S, Vonka V

机构信息

Department of Experimental Virology, Institute of Sera and Vaccines, Prague, Czechoslovakia.

出版信息

Arch Virol. 1990;113(3-4):283-9. doi: 10.1007/BF01316681.

DOI:10.1007/BF01316681
PMID:2222186
Abstract

Recombinant vaccinia virus expressing the middle hepatitis B virus surface antigen was incapable of inducing marked antibody response against the S and pre-S2 antigenic specifities in mice. However, mice immunized with this virus produced antibodies to both these antigens after the following administration of subtreshold doses of plasmatic hepatitis B surface antigen.

摘要

表达乙型肝炎病毒表面中蛋白抗原的重组痘苗病毒无法在小鼠中诱导出针对S抗原和前S2抗原特异性的显著抗体反应。然而，用这种病毒免疫的小鼠在随后接种亚阈值剂量的血浆乙型肝炎表面抗原后，产生了针对这两种抗原的抗体。

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Priming effect of recombinant vaccinia virus coding for the middle hepatitis B surface antigen.编码乙型肝炎表面抗原中蛋白的重组痘苗病毒的启动效应
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2
Hepatitis B virus proteins expressed by recombinant vaccinia viruses: influence of preS2 sequence on expression surface and nucleocapsid proteins in human diploid cells.重组痘苗病毒表达的乙型肝炎病毒蛋白：前S2序列对人二倍体细胞中表面蛋白和核衣壳蛋白表达的影响
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3
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本文引用的文献

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Recognition of influenza virus proteins by cytotoxic T lymphocytes.细胞毒性T淋巴细胞对流感病毒蛋白的识别。
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Selective synthesis and secretion of particles composed of the hepatitis B virus middle surface protein directed by a recombinant vaccinia virus: induction of antibodies to pre-S and S epitopes.由重组痘苗病毒指导的乙型肝炎病毒中表面蛋白组成颗粒的选择性合成与分泌：针对前S和S表位的抗体诱导
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