Rossol'ko G N, Ivanova V F, Puzyrev A A
Arkh Anat Gistol Embriol. 1990 May;98(5):55-61.
By means of light, electron microscopy and morphometry methods contents and structural organization of endocrinocytes have been investigated in gastric glands of rats, to whom testosterone propionate has been injected for 5, 10, 15, 20 days. The hormone produces certain stimulating effect on the endocrine apparatus function. During the first stages of the experiment most of the endocrinocytes are at the state of active secretion; this is testified as a decreasing composition of histochemically revealed cells in epithelium and their degranulation. During the following stages the process of synthesis is activated in the cells and their amount increases. Appearance of numerous agranular, poorly differentiated endocrinocytes and exo-endocrine cells demonstrates certain intensification of cytogenesis of endocrinocytes in the gastric epithelium. The changes observed are considered as adaptive, directed to stabilize homeostasis, when the hormonal balance is disturbed.
通过光学显微镜、电子显微镜和形态测量学方法，对注射丙酸睾酮5、10、15、20天的大鼠胃腺内分泌细胞的内容物和结构组织进行了研究。该激素对内分泌器官功能产生一定的刺激作用。在实验的最初阶段，大多数内分泌细胞处于活跃分泌状态；这可通过上皮组织中组织化学显示细胞的组成减少及其脱颗粒得到证实。在随后的阶段，细胞内的合成过程被激活，其数量增加。大量无颗粒、低分化的内分泌细胞和外分泌细胞的出现表明胃上皮内分泌细胞的细胞生成有一定增强。观察到的这些变化被认为是适应性的，旨在在内分泌平衡受到干扰时稳定体内稳态。
