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都柏林念珠菌性眼内炎:北美首例病例。

Candida dubliniensis endophthalmitis: first case in North America.

作者信息

Espinosa-Heidmann Diego G, McMillan Brian D, Lasala P Rocco, Stanley Jonathan, Larzo Cristoforo R

机构信息

Department of Ophthalmology, School of Medicine, West Virginia University Eye Institute, 1 Stadium Drive, Morgantown, WV 26505, USA.

出版信息

Int Ophthalmol. 2012 Feb;32(1):41-5. doi: 10.1007/s10792-011-9499-8. Epub 2012 Jan 6.

Abstract

To report an unusual case of endogenous fungal endophthalmitis due to Candida dubliniensis. Interventional case report of a 27-year-old immunocompetent male with loss of vision, dense vitritis, and chorioretinal infiltrates, who underwent a diagnostic pars plana vitrectomy. Microbiology cultures obtained by a diagnostic vitrectomy were positive for the growth of C. dubliniensis. This infectious process was then appropriately treated with intravitreal amphotericin B and systemic fluconazole with resolution of the endophthalmitis. Endogenous fungal endophthalmitis is a condition that can masquerade other more common causes of endophthalmitis. Atypical cases of endophthalmitis may benefit from diagnostic pars plana vitrectomy for prompt diagnosis and treatment.

摘要

报告一例由都柏林念珠菌引起的罕见内源性真菌性眼内炎病例。对一名27岁免疫功能正常、视力丧失、玻璃体浓密混浊及脉络膜视网膜浸润的男性患者进行了诊断性玻璃体切割术的介入性病例报告。诊断性玻璃体切割术获得的微生物培养结果显示都柏林念珠菌生长阳性。随后采用玻璃体内注射两性霉素B和全身应用氟康唑对该感染过程进行了适当治疗,眼内炎得以消退。内源性真菌性眼内炎可能会伪装成其他更常见的眼内炎病因。非典型性眼内炎病例可能受益于诊断性玻璃体切割术以实现快速诊断和治疗。

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