在牛病毒性腹泻病毒制剂中检测到三种多肽。
Detection of three polypeptides in preparations of bovine viral diarrhoea virus.
作者信息
Matthaeus W
出版信息
Arch Virol. 1979;59(4):299-305. doi: 10.1007/BF01317470.
Radiolabelled bovine viral diarrhoea/mucosal disease virus (BVDV) strains NADL and Oregon C24V were purified by different steps. Following immunoprecipitation, electrophoresis in SDS-polyacrylamide gels revealed three BVDV structural polypeptides with molecular weights of 57 (VP1), 44 (VP2), and 34 (VP3) kd. The two larger BVDV polypeptides VP1 and VP2 were found to be glycosylated (gp57, gp44). The data obtained on BVDV structural proteins demonstrate common features with hog cholera virus and indicate a common grouping with the family Togaviridae.
用不同步骤纯化放射性标记的牛病毒性腹泻/黏膜病病毒（BVDV）毒株NADL和俄勒冈C24V。免疫沉淀后，SDS-聚丙烯酰胺凝胶电泳显示出三种分子量分别为57（VP1）、44（VP2）和34（VP3）kd的BVDV结构多肽。发现两种较大的BVDV多肽VP1和VP2是糖基化的（gp57，gp44）。关于BVDV结构蛋白获得的数据表明其与猪霍乱病毒有共同特征，并表明与披膜病毒科属于同一类群。
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