Calabrò Rocco Salvatore, Baglieri Annalisa, Ferlazzo Edoardo, Passari Smeralda, Marino Silvia, Bramanti Placido
IRCCS Centro Neurolesi ‘Bonino-Pulejo’, Messina, Italy.
Neurocase. 2012;18(6):514-20. doi: 10.1080/13554794.2011.633530. Epub 2012 Jan 6.
We reported a case of an elderly female patient affected by musical hallucinations (MHs) as the unique symptom of a right temporal ischemic stroke. A functional magnetic resonance imaging examination was performed in the patient and in five age- and sex-matched normal controls (NC) to detect the complex neural substrate subserving MHs in such a context. Although an activation pattern involving the primary auditory cortex and the temporal associative areas bilaterally was found in the patient and NC, a significant increased activation mostly located in right temporal cortex (in the ischemic area), was observed in the patient. Further functional neuroimaging studies should be performed to detect the complex neural pathways underlying MHs and to find out differences between these hallucinations and real music perception.
我们报告了一例老年女性患者，其受音乐幻觉（MHs）影响，这是右侧颞叶缺血性中风的唯一症状。对该患者以及五名年龄和性别匹配的正常对照者（NC）进行了功能磁共振成像检查，以检测在这种情况下支持MHs的复杂神经基质。尽管在患者和NC中均发现了双侧涉及初级听觉皮层和颞叶联合区的激活模式，但在患者中观察到主要位于右侧颞叶皮层（缺血区域）的显著激活增加。应进行进一步的功能神经影像学研究，以检测MHs背后的复杂神经通路，并找出这些幻觉与真实音乐感知之间的差异。
