Department of Chemistry, University of California, Davis, One Shields Ave, Davis, CA 95616, USA.
Curr Opin Biotechnol. 2012 Oct;23(5):744-50. doi: 10.1016/j.copbio.2011.12.019. Epub 2012 Jan 4.
Global energy and environmental concerns have stimulated increased efforts in synthesizing petroleum-derived products from renewable resources. Biological production of metabolites for fuel is increasingly becoming a feasible, renewable, environmentally sound alternative. However, many of these chemicals are not highly produced in any known native organism. Here we review the current progress of modifying microorganisms with heterogeneous elements for the production of biofuels. This strategy has been extensively employed in a variety of hosts for the development of production of various alcohols, fatty acids, alkenes and alkanes.
全球能源和环境问题促使人们加大力度，从可再生资源中合成石油衍生产品。生物生产代谢产物作为燃料正日益成为一种可行的、可再生的、环境友好的替代方案。然而，这些化学物质中的许多在任何已知的天然生物中都没有大量产生。在这里，我们综述了利用异质元素修饰微生物以生产生物燃料的最新进展。该策略已广泛应用于各种宿主中，以开发各种醇、脂肪酸、烯烃和烷烃的生产。
