Vezia V, Renacco E, Castelain P Y, Caperan A, Lanza M, Pastor J
Pharmacie Hôpitaux Sud, Hôpital de Sainte-Marguerite.
Allerg Immunol (Paris). 1990 Sep;22(7):285-6.
Kathon is an anti-microbial agent that is used as a preservative in cosmetics and bodily hygiene products. At the recommended levels of usage Kathon is innocuous and has a recognised efficacy. Nevertheless, following reappearance of contact allergic eczemas due to cosmetics and bodily hygiene products different authors have reported increase in sensitisation to it. We have met the same problems in the Service de Dermatology++ of the Hospital Sainte Marguerite at Marseille and we wished to make a deeper examination of the question and to ascertain whether the current cosmetics contained Kathon CG. For this we have developed a technique of liquid chromatography and tested 44 creams. Eight contained Kathon CG, of which 2 were responsible for contact eczema in patients.
凯松是一种抗菌剂，用作化妆品和身体护理产品中的防腐剂。在推荐使用水平下，凯松是无害的且具有公认的功效。然而，由于化妆品和身体护理产品导致的接触性过敏性湿疹再次出现后，不同的作者报告了对其致敏性增加的情况。我们在马赛圣玛格丽特医院皮肤科也遇到了同样的问题，我们希望对这个问题进行更深入的研究，并确定当前的化妆品是否含有凯松CG。为此，我们开发了一种液相色谱技术，并测试了44种面霜。其中8种含有凯松CG，其中2种导致了患者的接触性湿疹。
