前列腺癌患者骨转移的动态对比增强磁共振成像表现
Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer.
作者信息
Kayhan Arda, Yang Cheng, Soylu Fatma Nur, Lakadamyalı Hatice, Sethi Ila, Karczmar Gregory, Stadler Walter, Oto Aytekin
机构信息
Arda Kayhan, Fatma Nur Soylu, Hatice Lakadamyalı, Ila Sethi, Gregory Karczmar, Aytekin Oto, Department of Radiology, University of Chicago, Chicago, IL 60637, United States.
出版信息
World J Radiol. 2011 Oct 28;3(10):241-5. doi: 10.4329/wjr.v3.i10.241.
Abstract
AIM
To evaluate the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) findings of bone metastasis in prostate cancer patients.
METHODS
Sixteen men with a diagnosis of metastatic prostate cancer to bones were examined with DCE-MRI at 1.5 Tesla. The mean contrast agent concentration vs time curves for bone metastasis and normal bone were calculated and K(trans) and ve values were estimated and compared.
RESULTS
An early significant enhancement (wash-out: n = 6, plateau: n = 8 and persistent: n = 2) was detected in all bone metastases (n = 16). Bone metastasis from prostate cancer showed significant enhancement and high K(trans) and ve values compared to normal bone which does not enhance in the elderly population. The mean K(trans) was 0.101/min and 0.0051/min (P < 0.001), the mean ve was 0.141 and 0.0038 (P < 0.001), for bone metastases and normal bone, respectively.
CONCLUSION
DCE-MRI and its quantitative perfusion parameters may have a role in improving the detection of skeletal metastasis in prostate cancer patients.
摘要
目的
评估前列腺癌患者骨转移的动态对比增强磁共振成像（DCE-MRI）表现。
方法
对16例诊断为前列腺癌骨转移的男性患者进行1.5特斯拉的DCE-MRI检查。计算骨转移灶和正常骨的平均对比剂浓度-时间曲线，并估算和比较K(trans)及ve值。
结果
在所有16处骨转移灶中均检测到早期显著强化（廓清型：6处，平台型：8处，持续型：2处）。与老年人群中不强化的正常骨相比，前列腺癌骨转移灶表现出显著强化以及较高的K(trans)和ve值。骨转移灶和正常骨的平均K(trans)分别为0.101/min和0.0051/min（P < 0.001），平均ve分别为0.141和0.0038（P < 0.001）。
结论
DCE-MRI及其定量灌注参数可能有助于提高前列腺癌患者骨转移的检测率。
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本文引用的文献
1
Cancer statistics, 2009.2009年癌症统计数据。
CA Cancer J Clin. 2009 Jul-Aug;59(4):225-49. doi: 10.3322/caac.20006. Epub 2009 May 27.
2
Reproducibility assessment of a multiple reference tissue method for quantitative dynamic contrast enhanced-MRI analysis.用于定量动态对比增强磁共振成像分析的多参考组织方法的可重复性评估
Magn Reson Med. 2009 Apr;61(4):851-9. doi: 10.1002/mrm.21912.
3
Imaging anti-angiogenic treatment response with DCE-VCT, DCE-MRI and DWI in an animal model of breast cancer bone metastasis.用 DCE-VCT、DCE-MRI 和 DWI 对乳腺癌骨转移动物模型进行抗血管生成治疗反应的成像研究。
Eur J Radiol. 2010 Feb;73(2):280-7. doi: 10.1016/j.ejrad.2008.10.020. Epub 2008 Dec 12.
4
Multiple reference tissue method for contrast agent arterial input function estimation.用于造影剂动脉输入函数估计的多参考组织方法
Magn Reson Med. 2007 Dec;58(6):1266-75. doi: 10.1002/mrm.21311.
5
Magnetic resonance imaging of the axial skeleton for detecting bone metastases in patients with high-risk prostate cancer: diagnostic and cost-effectiveness and comparison with current detection strategies.高危前列腺癌患者轴向骨骼的磁共振成像用于检测骨转移：诊断及成本效益分析以及与当前检测策略的比较
J Clin Oncol. 2007 Aug 1;25(22):3281-7. doi: 10.1200/JCO.2006.09.2940.
6
Detection of occult spinal cord compression with magnetic resonance imaging of the spine.
Clin Oncol (R Coll Radiol). 2007 Sep;19(7):528-31. doi: 10.1016/j.clon.2007.04.001. Epub 2007 May 17.
7
Dynamic contrast-enhanced perfusion MR imaging of diseased vertebrae: analysis of three parameters and the distribution of the time-intensity curve patterns.病变椎体的动态对比增强灌注磁共振成像：三个参数及时间-强度曲线模式分布的分析
Skeletal Radiol. 2005 Oct;34(10):632-8. doi: 10.1007/s00256-005-0949-0. Epub 2005 Aug 10.
8
Detection of malignant bone marrow involvement with dynamic contrast-enhanced magnetic resonance imaging.利用动态对比增强磁共振成像检测恶性骨髓浸润
Ann Oncol. 2003 Jan;14(1):152-8. doi: 10.1093/annonc/mdg007.
9
Metastasis to bone: causes, consequences and therapeutic opportunities.骨转移：病因、后果及治疗机遇
Nat Rev Cancer. 2002 Aug;2(8):584-93. doi: 10.1038/nrc867.
10
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J Magn Reson Imaging. 2002 Mar;15(3):308-14. doi: 10.1002/jmri.10063.
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