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子宫内膜癌患者:肿瘤行为和治疗策略改变之前的队列研究。

Endometrial cancer patients: a cohort previous to changes in tumour behaviour and treatment strategies.

作者信息

Tournois F K L, Mertens H J M M

机构信息

Department of Obstetrics and Gynecology, Orbis Medical Centre, Postbus 5500, 6130MB Sittard, The Netherlands.

出版信息

ISRN Obstet Gynecol. 2011;2011:950460. doi: 10.5402/2011/950460. Epub 2011 Dec 18.

Abstract

Nowadays, the incidence of endometrial cancer is rising, especially of high-grade endometrial tumours. Recently, the FIGO classification of endometrial cancer has changed worldwide. Besides that, treatment strategies are changing. The purpose of this study was to analyse the adherence to the national guidelines of cancer treatment and to analyse patterns of disease relapse and survival. We focused on a group of patients (n = 191) with endometrial cancer, in a time period in which new treatment strategies are not yet completely implemented. Because of multiple upcoming changes in patient characteristics, tumour classification, as well as treatment regimens, a more heterogeneous cohort of patients diagnosed with endometrial cancer will appear. From now on, all those changes will have their effects on the followup of conventional endometrial cancer treatment. In our opinion, it is, therefore, valuable to have the current, more homogenous, cohort clearly described.

摘要

如今,子宫内膜癌的发病率正在上升,尤其是高级别子宫内膜肿瘤。最近,全球范围内子宫内膜癌的国际妇产科联盟(FIGO)分类发生了变化。除此之外,治疗策略也在改变。本研究的目的是分析癌症治疗国家指南的遵循情况,并分析疾病复发和生存模式。我们聚焦于一组子宫内膜癌患者(n = 191),这一时期新的治疗策略尚未完全实施。由于患者特征、肿瘤分类以及治疗方案即将发生多种变化,将会出现一个诊断为子宫内膜癌的更具异质性的队列。从现在起,所有这些变化都将对传统子宫内膜癌治疗的随访产生影响。因此,我们认为清晰描述当前这个更具同质性的队列是有价值的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1555/3246774/05e8ef714f16/OBGYN2011-950460.001.jpg

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