Department of Chemistry and Biochemistry, California Polytechnic State University, San Luis Obispo, California 93407, USA.
Anal Chem. 2012 Feb 7;84(3):1579-85. doi: 10.1021/ac202837s. Epub 2012 Jan 9.
This article introduces fully enclosed microfluidic paper-based analytical devices (microPADs) fabricated by printing toner on the top and bottom of the devices using a laser printer. Enclosing paper-based microfluidic channels protects the channels from contamination, contains and protects reagents stored on the device, contains fluids within the channels so that microPADs can be handled and operated more easily, and reduces evaporation of solutions from the channels. These benefits extend the capabilities of microPADs for applications as low-cost point-of-care diagnostic devices.
本文介绍了一种使用激光打印机在器件顶部和底部打印墨粉来制造全封闭微流控纸基分析器件（microPAD）的方法。封闭纸基微流道可以防止通道受到污染，容纳并保护器件上储存的试剂，将流体限制在通道内，从而使 microPAD 更易于操作和处理，并减少通道中溶液的蒸发。这些优点扩展了 microPAD 在低成本即时诊断设备等应用中的功能。
