Nanoscience Research Laboratory, School of Nano Science and Technology, National Institute of Technology Calicut, Calicut, Kerala, India.
Colloids Surf B Biointerfaces. 2012 May 1;93:143-7. doi: 10.1016/j.colsurfb.2011.12.028. Epub 2011 Dec 31.
Chitosan gold nanocomposite (CGNC) was synthesized in a single step process and the pH dependent properties of the composite were investigated. The structure of the polymer was pH dependent and gelation of the polymer observed at pH 4-5. Transmission electron microscopy (TEM) analysis showed that the distribution of gold nanoparticles within unit area varied with the gelation of the polymer, without affecting the size of the nanoparticles. The resulting CGNC system was explored for its use as a sensor for the detection of lead. It was found that lead could be detected at a concentration of 1 μM by absorption spectroscopy. The CGNC was electrodeposited on a gold electrode and the deposited film was used for the detection of lead using cyclic voltammetry. Lead could be detected with a detection limit of 10 μM. The fabrication reproducibility for four sensor electrodes showed a relative standard deviation (RSD) of 2.09% for the determination of 1 mM lead nitrate. The developed sensor system showed high reproducibility, stability and satisfactory selectivity.
壳聚糖金纳米复合材料（CGNC）在一步法过程中合成，并研究了其对 pH 值的依赖特性。该聚合物的结构与 pH 值有关，在 pH4-5 时观察到聚合物的凝胶化。透射电子显微镜（TEM）分析表明，金纳米粒子在单位面积内的分布随聚合物的凝胶化而变化，而不影响纳米粒子的大小。研究了所得 CGNC 体系作为用于检测铅的传感器的用途。发现通过吸收光谱可以在 1 μM 的浓度下检测到铅。CGNC 被电沉积在金电极上，并用循环伏安法检测沉积膜中的铅。检测限为 10 μM。四个传感器电极的制备重现性表明，对于 1 mM 硝酸铅的测定，相对标准偏差（RSD）为 2.09%。所开发的传感器系统具有高重现性、稳定性和令人满意的选择性。
