Institut National de la Recherche Scientifique - Institut Armand-Frappier, Laval, Quebec, Canada H7V 1B7.
Sci Total Environ. 2012 Feb 15;417-418:98-107. doi: 10.1016/j.scitotenv.2011.11.084. Epub 2012 Jan 10.
Seven mother-pup pairs of harp seal (Phoca groenlandica) were sampled during the lactation season near Magdalen Islands, QC, Canada. The blubber and serum of pups and mothers as well as the milk of mothers were analyzed for polybrominated diphenyl ethers and several chlorinated persistent organic pollutants (POPs) to evaluate their transfer prior to weaning. Principal component analysis demonstrated significant variations in contaminant distribution patterns between seal tissues of mothers and pups. The selectivity in the transfer of POPs between mothers and pups appeared mainly driven by their log K(ow) (octanol/water partition coefficient). The most selective transfer step for the POPs examined occurred between the blubber and the serum of the mother. A novel approach to examine temporal changes of POP concentrations in tissues of seals which take into account the contamination of mothers was developed. A general decrease of POP concentrations in pup tissues throughout lactation may suggest a growth dilution. A concomitant rise of POP concentrations was observed in maternal blubber and serum and in milk as lactation progresses. The intensive offloading of contaminants via lactation constitutes a major but selective excretory route for reproductive female seals and also a significant route of exposure for suckling pup seals.
在加拿大魁北克省马格达伦群岛附近的哺乳期，对 7 对海豹母子进行了采样。分析了幼崽和母海豹的脂肪和血清以及母海豹的乳汁中的多溴二苯醚和几种氯化持久性有机污染物（POPs），以评估它们在断奶前的转移情况。主成分分析表明，母海豹和幼崽海豹组织中的污染物分布模式存在显著差异。POPs 在母海豹和幼崽海豹之间的转移选择性主要由它们的 log K(ow)（辛醇/水分配系数）决定。在所检查的 POPs 中，最具选择性的转移步骤发生在母海豹的脂肪和血清之间。开发了一种新的方法来检查海豹组织中 POP 浓度随时间的变化，该方法考虑了母亲的污染情况。哺乳期内幼崽组织中 POP 浓度的普遍下降可能表明生长稀释。随着哺乳期的进展，母海豹的脂肪和血清以及乳汁中的 POP 浓度同时升高。通过哺乳期大量排出污染物是繁殖雌性海豹的主要但选择性的排泄途径，也是幼崽海豹暴露的重要途径。
