Cadelis G, Cordel N, Coquart N, Etienne N, Macal M
Service de pneumologie, CHU de Pointe-à-Pitre, 97159 Pointe-à-Pitre cedex, Guadeloupe.
Rev Mal Respir. 2012 Jan;29(1):13-20. doi: 10.1016/j.rmr.2011.11.002. Epub 2011 Dec 14.
Sarcoidosis is a systemic granulomatosis of unknown origin with a high incidence in the Afro-American population. There is no epidemiologic data regarding Afro-Caribbean population. The aim of our study was to evaluate the incidence and epidemiologic data of the disease, on the island of Guadeloupe, (French West Indies; 402 500 inhabitants, 90% Afro-Caribbean people) during the 13-years period between 1/01/1997 and 31/12/2009.
We performed a retrospective study including exclusively patients with a diagnosis of sarcoidosis confirmed by histological examination of the involved tissues.
One hundred and thirteen patients were enrolled in the study. One hundred and eleven patients (98%) were black Caribbean of African European descent. Eighteen patients (16%) were more than 65 years old. The crude annual incidence over the study period was 2.9 cases per 100,000 inhabitants (IC 95%: [2,4-3,4]). The main localization of the disease was the chest (89%). Radiographic stages were distributed as following: I (31%), II (39%), III (15%), IV (2%).
Our study showed a low incidence rate of sarcoidosis on the island of Guadeloupe over the study period with a high rate of old patients.
结节病是一种病因不明的全身性肉芽肿病，在非裔美国人中发病率较高。目前尚无关于非裔加勒比人群的流行病学数据。我们研究的目的是评估1997年1月1日至2009年12月31日这13年间，瓜德罗普岛（法属西印度群岛；402,500居民，90%为非裔加勒比人）该疾病的发病率及流行病学数据。
我们进行了一项回顾性研究，仅纳入经受累组织组织学检查确诊为结节病的患者。
113名患者纳入研究。111名患者（98%）为非洲裔欧洲血统的加勒比黑人。18名患者（16%）年龄超过65岁。研究期间的粗年发病率为每10万居民2.9例（95%置信区间：[2.4 - 3.4]）。该疾病的主要发病部位是胸部（89%）。影像学分期分布如下：I期（31%），II期（39%），III期（15%），IV期（2%）。
我们的研究表明，在研究期间瓜德罗普岛结节病的发病率较低，老年患者比例较高。
